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一名接受反复动静脉内瘘插管的血液透析患者发生伴有二尖瓣赘生物的路邓葡萄球菌感染性心内膜炎:病例报告

Staphylococcus lugdunensis Infective Endocarditis With Mitral Valve Vegetations in a Hemodialysis Patient With Recurrent Arteriovenous Fistula Cannulation: A Case Report.

作者信息

Mousa Aliaa, Ghazy Ahmed, Kakhktsyan Tigran, Chepenko Kateryna, Young Kristopher

机构信息

Internal Medicine, Capital Health Regional Medical Center, Trenton, USA.

Cardiology, Capital Health Regional Medical Center, Trenton, USA.

出版信息

Cureus. 2023 Jun 1;15(6):e39853. doi: 10.7759/cureus.39853. eCollection 2023 Jun.

DOI:10.7759/cureus.39853
PMID:37404404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10314977/
Abstract

Infective endocarditis is a severe medical condition that occurs when the endocardium of the heart gets infected by different microorganisms, including coagulase-negative staphylococci such as . The source of infection is often related to procedures done in the groin area, such as femoral catheterization for cardiac catheterization, vasectomy, or central line placement in an already infected mitral or aortic valve. Herein, we are discussing a case of a 55-year-old female with a past medical history of end-stage renal disease on hemodialysis with a history of recurrent cannulation of her arteriovenous (AV) fistula. She presented with fever, myalgia, and generalized weakness, and was later found to have bacteremia and infective endocarditis with mitral valve vegetations, for which the patient was transferred to the mitral valve specialized center for mitral valve replacement. This case acts as a reminder to consider recurrent cannulation of the AV fistula as one of the potential ports of entry of to the body.

摘要

感染性心内膜炎是一种严重的医学病症,当心脏的内膜被不同微生物感染时就会发生,这些微生物包括凝固酶阴性葡萄球菌等。感染源通常与腹股沟区进行的操作有关,如心脏导管插入术的股动脉导管插入、输精管切除术,或在已感染的二尖瓣或主动脉瓣中放置中心静脉导管。在此,我们正在讨论一名55岁女性的病例,她有终末期肾病并接受血液透析的病史,且有动静脉(AV)瘘反复插管的病史。她出现发热、肌痛和全身无力,后来被发现患有菌血症和伴有二尖瓣赘生物的感染性心内膜炎,为此患者被转至二尖瓣专科中心进行二尖瓣置换。这个病例提醒我们要将AV瘘的反复插管视为细菌进入人体的潜在入口之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a381/10314977/26c239e49d77/cureus-0015-00000039853-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a381/10314977/26c239e49d77/cureus-0015-00000039853-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a381/10314977/26c239e49d77/cureus-0015-00000039853-i01.jpg

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本文引用的文献

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Infective Endocarditis in Patients on Chronic Hemodialysis.慢性血液透析患者的感染性心内膜炎。
J Am Coll Cardiol. 2021 Apr 6;77(13):1629-1640. doi: 10.1016/j.jacc.2021.02.014.
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Endocarditis due to Staphylococcus lugdunensis-a retrospective national registry-based study.中文译文:凝固酶阴性葡萄球菌性心内膜炎——一项基于全国回顾性登记研究。
Eur J Clin Microbiol Infect Dis. 2021 May;40(5):1103-1106. doi: 10.1007/s10096-020-04134-w. Epub 2020 Dec 30.
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Current AATS guidelines on surgical treatment of infective endocarditis.美国胸外科医师协会(AATS)目前关于感染性心内膜炎外科治疗的指南。
Ann Cardiothorac Surg. 2019 Nov;8(6):630-644. doi: 10.21037/acs.2019.10.05.
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Staphylococcus lugdunensis from gluteal abscess to destructive native triple valve endocarditis.从臀肌脓肿到破坏性自体三尖瓣心内膜炎的路邓葡萄球菌感染
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Cureus. 2018 Apr 12;10(4):e2469. doi: 10.7759/cureus.2469.
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Physiopathological approach to infective endocarditis in chronic hemodialysis patients: left heart versus right heart involvement.慢性血液透析患者感染性心内膜炎的病理生理学研究:左心与右心受累情况
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Expert Rev Anti Infect Ther. 2011 Oct;9(10):901-7. doi: 10.1586/eri.11.110.
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Clin Infect Dis. 2011 Feb 1;52(3):285-92. doi: 10.1093/cid/cir034.
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