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发展中国家的专业儿科心脏重症监护病房:它能改善治疗结果吗?

Dedicated pediatric cardiac intensive care unit in a developing country: Does it improve the outcome?

作者信息

Balachandran Rakhi, Nair Suresh G, Gopalraj Sunil S, Vaidyanathan Balu, Kumar R Krishna

机构信息

Department of Anesthesia, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala, India.

出版信息

Ann Pediatr Cardiol. 2011 Jul;4(2):122-6. doi: 10.4103/0974-2069.84648.

Abstract

INTRODUCTION AND AIM

Focussed cardiac intensive care is known to produce better outcomes. We have evaluated the benefits of a dedicated Pediatric Cardiac Intensive Care Unit (PCICU) in the early postoperative outcomes of patients undergoing surgery for congenital heart disease.

METHODS

Prospectively collected data of 634 consecutive patients who underwent congenital heart surgery from September 2008 to September 2009 were analyzed. Midway through this period a dedicated PCICU was started. The patients who were treated in this new PCICU formed the study group (Group B, n = 318). The patients who were treated in a common postoperative cardiac surgery ICU formed the control group (Group A, n = 316). Early postoperative outcomes between the two groups were compared.

RESULTS

The two groups were comparable with respect to demographic data and intraoperative variables. The duration of mechanical ventilation in the dedicated pediatric cardiac ICU group (32.22 ± 52.02 hours) was lower when compared with the combined adult and pediatric surgery ICU group (42.92 ± 74.24 hours, P= 0.04). There was a shorter duration of ICU stay in the dedicated pediatric cardiac ICU group (2.69 ± 2.9 days vs. 3.43 ± 3.80 days, P = 0.001). The study group also showed a shorter duration of inotropic support and duration of invasive lines. The incidence of blood stream infections was also lower in the dedicated pediatric ICU group (5.03 vs. 9.18%, P = 0.04). A subgroup analysis of neonates and infants <1 year showed that the advantages of a dedicated pediatric intensive care unit were more pronounced in this group of patients.

CONCLUSIONS

Establishment of a dedicated pediatric cardiac intensive care unit has shown better outcomes in terms of earlier extubation, de-intensification, and discharge from the ICU. Blood stream infections were also reduced.

摘要

引言与目的

已知专注于心衰的重症监护可产生更好的治疗效果。我们评估了设立专门的小儿心脏重症监护病房(PCICU)对先天性心脏病手术患者术后早期治疗效果的益处。

方法

分析了2008年9月至2009年9月期间连续634例行先天性心脏病手术患者的前瞻性收集数据。在此期间中途设立了专门的PCICU。在这个新的PCICU接受治疗的患者组成研究组(B组,n = 318)。在普通的心脏外科术后重症监护病房接受治疗的患者组成对照组(A组,n = 316)。比较了两组术后早期的治疗效果。

结果

两组在人口统计学数据和术中变量方面具有可比性。专门的小儿心脏重症监护病房组的机械通气时间(32.22 ± 52.02小时)低于成人与小儿联合外科重症监护病房组(42.92 ± 74.24小时,P = 0.04)。专门的小儿心脏重症监护病房组的重症监护病房住院时间更短(2.69 ± 2.9天对3.43 ± 3.80天,P = 0.001)。研究组还显示出更短的血管活性药物支持时间和侵入性管路留置时间。专门的小儿重症监护病房组的血流感染发生率也更低(5.03%对9.18%,P = 0.04)。对新生儿和1岁以下婴儿的亚组分析表明,专门的小儿重症监护病房对这组患者的优势更为明显。

结论

设立专门的小儿心脏重症监护病房在更早拔除气管插管、降低治疗强度和从重症监护病房出院方面显示出更好的治疗效果。血流感染也有所减少。

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