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68例难治性支原体肺炎(RMPP)临床报告

[Clinical report on 68 cases of refractory mycoplasma pneumoniae pneumonia (RMPP)].

作者信息

Wang Lei, Duan Jian-Hua

机构信息

Beijing Children's Attached Hospital of Capital Medical University, 100045, China.

出版信息

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Jun;25(3):224-6.

Abstract

OBJECTIVE

To summarize the early diagnose and treatment approaches of Refractory Mycoplasma Pneumoniae Pneumonia (RMPP).

METHODS

Medical documents of 68 cases of RMPP were reviewed. Lab and radiology evident such as CBC, CRP, MP-IgM, X-ray, etc. were collected.

RESULTS

100% RMPP patients suffered from high fever. Positive sign of lung became clear with the development of the disease. Complications as impairment of liver function, cardiac function and rush developed in few patients. 2-4 rounds treatment of macrolides and Methyllprednisolone were necessary for RMPP while antibiotic may be considered when there were evidence of bacteria infection. Immunoglobulin was recommended to the patients when macrolides and steroid seemed ineffective. Bronchofibroscope played an active role regarding the diagnosis and treatment of RMPP.

CONCLUSION

Early diagnosis is crucial in RMPP. Combination of multitreatment approaches is the key to cure RMPP.

摘要

目的

总结难治性支原体肺炎(RMPP)的早期诊断及治疗方法。

方法

回顾68例RMPP患者的病历资料,收集血常规、C反应蛋白、肺炎支原体IgM、X线等实验室及影像学证据。

结果

100%的RMPP患者有高热。肺部阳性体征随病情发展逐渐明显。少数患者出现肝功能、心功能损害及皮疹等并发症。RMPP患者需2 - 4个疗程的大环内酯类药物及甲泼尼龙治疗,如有细菌感染证据可考虑加用抗生素。当大环内酯类药物和激素治疗无效时,建议使用免疫球蛋白。支气管纤维镜在RMPP的诊断和治疗中发挥积极作用。

结论

早期诊断对RMPP至关重要。综合多种治疗方法是治愈RMPP的关键。

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