Rehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Support Care Cancer. 2012 Aug;20(8):1839-47. doi: 10.1007/s00520-011-1285-7. Epub 2011 Oct 7.
African-American women are more likely than white women to have functional impairments after breast cancer (BC) surgery; however, no differences were found in self-reported health status surveys at 12+ months postsurgery.
This analysis compared white and African-American BC survivors' (BCS) health status, health-related quality of life, and the occurrence of physical impairments after BC treatment.
One hundred sixty-six women (130 white, 28 African-American, 8 other) were assessed for impairments preoperatively and at 1, 3, 6, 9, and 12+ months postsurgery. Health status was assessed at 12+ months using the Short Form Health Survey (SF36v2™). Analysis of variance estimated differences between groups for health status and impairment occurrence.
No differences were found between groups for BC type, stage, grade, or tumor size; surgery type; or number of lymph nodes sampled. African-American BCS had more estrogen/progesterone receptor-negative tumors (p < 0.001; p = 0.036) and received radiation more frequently (p = 0.03). More African-American BCS were employed (p = 0.022) and reported higher rates of social activities (p = 0.011) but less recreational activities (p = 0.020) than white BCS. African-American BCS had higher rates of cording (p = 0.013) and lymphedema (p = 0.011) postoperatively. No differences were found in self-reported health status.
In a military healthcare system, where access to care is ubiquitous, there were no significant differences in many BC characteristics commonly attributed to race. African-American women had more ER/PR-negative tumors; however, no other BC characteristics differed between racial groups. African-American women exhibited more physical impairments, although their BC treatment only differed regarding radiation therapy. This suggests that African-American BCS may be at higher risk for physical impairments and should be monitored prospectively for early identification and treatment.
非裔美国女性在乳腺癌（BC）手术后出现功能障碍的可能性高于白人女性；然而，在手术后 12 个月及以上的自我报告健康状况调查中并未发现差异。
本分析比较了白人和非裔美国乳腺癌幸存者（BCS）的健康状况、健康相关生活质量以及乳腺癌治疗后身体损伤的发生情况。
166 名女性（130 名白人，28 名非裔美国人，8 名其他种族）在术前以及术后 1、3、6、9 和 12 个月+进行损伤评估。使用健康调查简表（SF36v2™）在术后 12 个月评估健康状况。方差分析估计了组间健康状况和损伤发生的差异。
在 BC 类型、分期、分级或肿瘤大小、手术类型或取样的淋巴结数量方面，组间均未发现差异。非裔美国 BCS 具有更多的雌激素/孕激素受体阴性肿瘤（p < 0.001；p = 0.036），并且更常接受放疗（p = 0.03）。更多的非裔美国 BCS 就业（p = 0.022），报告更高的社交活动率（p = 0.011），但更少的娱乐活动（p = 0.020），而非白人 BCS。非裔美国 BCS 术后发生排线（p = 0.013）和淋巴水肿（p = 0.011）的比率较高。自我报告的健康状况无差异。
在一个医疗保健系统中，获得医疗服务的机会普遍存在，许多与种族相关的乳腺癌特征在许多方面没有显著差异。非裔美国女性具有更多的 ER/PR 阴性肿瘤；然而，种族群体之间没有其他乳腺癌特征存在差异。非裔美国女性表现出更多的身体损伤，尽管她们的乳腺癌治疗仅在放疗方面有所不同。这表明非裔美国 BCS 可能面临更高的身体损伤风险，应进行前瞻性监测，以便及早发现和治疗。
