Cancer Survivorship Division, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2085-92. doi: 10.1158/1055-9965.EPI-11-0642.
The growing number of individuals living five or more years from cancer diagnosis underscores the importance of providing guidance about potential late treatment effects to clinicians caring for long-term cancer survivors. Late treatment effects are commonly experienced by cancer survivors, increase in prevalence with aging, produce substantial morbidity, and predispose to early mortality. Findings from survivorship research permit providers to anticipate health risks among predisposed survivors and facilitate their access to interventions to prevent, detect, or rehabilitate cancer-related morbidity. This article reviews the impact that survivorship research has made in defining clinical care guidelines and the challenges that remain in developing and translating research findings into health screening recommendations that can optimize the quality and duration of survival after cancer.
越来越多的癌症患者的生存时间超过五年,这凸显了为长期癌症幸存者的临床医生提供潜在晚期治疗效果指导的重要性。晚期治疗效果是癌症幸存者常见的问题,随着年龄的增长而普遍增加,会导致大量发病率,并导致早期死亡率增加。生存研究的结果使提供者能够预测易患幸存者的健康风险,并为他们提供预防、检测或康复与癌症相关发病率的干预措施提供便利。本文回顾了生存研究在定义临床护理指南方面所产生的影响,以及在制定和将研究结果转化为可优化癌症后生存质量和持续时间的健康筛查建议方面仍然存在的挑战。