The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.
作者信息
Thornalley P J
机构信息
Department of Chemistry and Biological Chemistry, University of Essex, Colchester, U.K.
出版信息
Biochem J. 1990 Jul 1;269(1):1-11. doi: 10.1042/bj2690001.
Abstract
摘要
相似文献
1
The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.乙二醛酶系统：对生物生命基本代谢途径进行功能表征的新进展。
Biochem J. 1990 Jul 1;269(1):1-11. doi: 10.1042/bj2690001.
2
[Glyoxalases in normal and neoplastic tissues (author's transl)].正常组织与肿瘤组织中的乙二醛酶（作者译）
Przegl Lek. 1980;37(4):425-8.
3
Modification of the glyoxalase system in human HL60 promyelocytic leukaemia cells during differentiation to neutrophils in vitro.人HL60早幼粒细胞白血病细胞在体外分化为中性粒细胞过程中乙二醛酶系统的修饰。
Biochim Biophys Acta. 1988 Sep 8;966(3):362-9. doi: 10.1016/0304-4165(88)90086-4.
4
5
Synthesis of S-lactoyl-glutathione using glyoxalase I bound to sepharose 4B.使用结合到琼脂糖4B上的乙二醛酶I合成S-乳酰谷胱甘肽。
Experientia. 1976 Nov 15;32(11):1382-3. doi: 10.1007/BF01937387.
6
A re-evaluation of studies on the distribution of glyoxalases in animal and tumour tissues.对乙二醛酶在动物和肿瘤组织中分布的研究的重新评估。
Int J Biochem. 1978;9(11):853-60. doi: 10.1016/0020-711x(78)90036-8.
7
Glyoxalase biochemistry.乙二醛酶生物化学
Biomol Concepts. 2015 Dec;6(5-6):401-14. doi: 10.1515/bmc-2015-0025.
8
The glyoxalase pathway: the first hundred years... and beyond.糖醛酸途径：第一个百年……及以后。
Biochem J. 2013 Jul 1;453(1):1-15. doi: 10.1042/BJ20121743.
9
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants.乙二醛酶走向绿色：乙二醛酶在植物中的作用不断扩展
Int J Mol Sci. 2017 Apr 24;18(4):898. doi: 10.3390/ijms18040898.
10
[Role of glyoxalases and methylglyoxal in cell proliferation and differentiation].[乙二醛酶和甲基乙二醛在细胞增殖与分化中的作用]
Postepy Hig Med Dosw. 1995;49(3):433-44.
引用本文的文献
1
Mitochondrial dysfunction by glyoxalase 1 deficiency disrupts definitive endoderm and alveolar development of human pluripotent stem cells.乙二醛酶1缺乏导致的线粒体功能障碍会破坏人类多能干细胞的定形内胚层和肺泡发育。
Exp Mol Med. 2025 Sep 1. doi: 10.1038/s12276-025-01524-y.
2
Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.乙二醛酶1基因在各类癌细胞中的表达免疫病理学：一项泛癌分析研究
Front Oncol. 2025 Jul 14;15:1610886. doi: 10.3389/fonc.2025.1610886. eCollection 2025.
3
Modelling the effects of elevated methylglyoxal levels on vascular and metabolic complications.模拟甲基乙二醛水平升高对血管和代谢并发症的影响。
Sci Rep. 2025 Feb 19;15(1):6025. doi: 10.1038/s41598-025-90661-5.
4
Genome-Wide Analysis and Expression Profiling of Glyoxalase Gene Families Under Abiotic Stresses in Cucumber ( L.).黄瓜（ L.）非生物胁迫下乙醛酸酶基因家族的全基因组分析和表达谱分析。
Int J Mol Sci. 2024 Oct 20;25(20):11294. doi: 10.3390/ijms252011294.
5
and encoding glyoxalase II improve tolerance of sp. PCC 6803 to methylglyoxal- and ethanol- induced oxidative stress by glyoxalase pathway.并且编码甘氨酸酶 II 可以通过甘氨酸酶途径提高 sp. PCC 6803 对甲基乙二醛和乙醇诱导的氧化应激的耐受性。
Appl Environ Microbiol. 2024 Nov 20;90(11):e0056424. doi: 10.1128/aem.00564-24. Epub 2024 Oct 21.
6
LasR-deficient mutants have increased methylglyoxal and hydrogen peroxide sensitivity due to low intracellular glutathione.由于细胞内谷胱甘肽含量低，LasR缺陷型突变体对甲基乙二醛和过氧化氢的敏感性增加。
bioRxiv. 2024 Sep 25:2024.09.25.615034. doi: 10.1101/2024.09.25.615034.
7
Lysine L-lactylation is the dominant lactylation isomer induced by glycolysis.赖氨酸L-乳酰化是糖酵解诱导产生的主要乳酰化异构体。
Nat Chem Biol. 2025 Jan;21(1):91-99. doi: 10.1038/s41589-024-01680-8. Epub 2024 Jul 19.
8
Novel anthraquinone amide derivatives as potential glyoxalase-I inhibitors.新型蒽醌酰胺衍生物作为潜在的醛糖还原酶 I 抑制剂。
J Med Life. 2024 Jan;17(1):87-98. doi: 10.25122/jml-2023-0257.
9
An overview on glycation: molecular mechanisms, impact on proteins, pathogenesis, and inhibition.糖基化概述：分子机制、对蛋白质的影响、发病机制及抑制作用
Biophys Rev. 2024 Apr 12;16(2):189-218. doi: 10.1007/s12551-024-01188-4. eCollection 2024 Apr.
10
Emerging and multifaceted potential contributions of polyphenols in the management of type 2 diabetes mellitus.多酚在2型糖尿病管理中的新兴及多方面潜在作用
World J Diabetes. 2024 Feb 15;15(2):154-169. doi: 10.4239/wjd.v15.i2.154.
本文引用的文献
1
On the distribution of glyoxalase and glutathione.论乙二醛酶与谷胱甘肽的分布
Biochem J. 1945;39(4):320-4. doi: 10.1042/bj0390320.
2
The mechanism of action of glyoxalase.乙二醛酶的作用机制。
J Biol Chem. 1951 Jun;190(2):685-96.
3
ENZYMATIC SYNTHESIS AND METABOLISM OF HYDROXYPYRUVIC ALDEHYDE.羟基丙酮酸醛的酶促合成与代谢
J Biol Chem. 1965 Feb;240:569-73.
4
STRUCTURE AND PROPERTIES OF A HOMOLOGUE OF GLUTATHIONE.谷胱甘肽同系物的结构与性质
Biochem J. 1963 Dec;89(3):471-8. doi: 10.1042/bj0890471.
5
6
Imidazole catalysis. II. Acyl transfer and the reactions of acetyl imidazole with water and oxygen anions.咪唑催化作用。II. 酰基转移以及乙酰咪唑与水和氧负离子的反应。
J Biol Chem. 1959 May;234(5):1272-9.
7
8
[Stereospecificity of glyoxalase II].[乙二醛酶II的立体特异性]
Biochem Z. 1956;328(4):239-44.
9
[Knowledge on glyoxalases].[关于乙二醛酶的知识]
Biochem Z. 1956;327(6):393-406.
10
Reactions of methylglyoxal with nucleic acids.甲基乙二醛与核酸的反应。
FEBS Lett. 1973 Jan 1;29(1):51-54. doi: 10.1016/0014-5793(73)80013-4.
Zotero 插件