Cetinkaya Merih, Ozkan Hilal, Celebi Solmaz, Köksal Nilgün, Hacimustafaoğlu Mustafa
Division of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Turk J Pediatr. 2011 Jul-Aug;53(4):441-4.
Human infection with H1N1 virus reached pandemic status by the spring of 2009. Consequently, the rates of morbidity and mortality related with H1N1 2009 infections have been reported to be higher in pregnant women. H1N1 viremia is rare in the mother, and the risk for transmission of H1N1 2009 influenza from mother to fetus is unknown. To our knowledge, the literature contains only one previous report of a premature infant with H1N1 2009 infection whose mother also had H1N1 2009 infection. Here, we report an H1N1 pandemic influenza 2009-positive female premature infant born at 32 weeks of gestation whose mother had a confirmed H1N1 2009 infection by real-time reverse transcriptase polymerase chain reaction (rRT-PCR). This case suggests that H1N1 2009 virus might be transmitted across the placenta, and therefore, all infants born to an H1N1 2009-positive mother must be evaluated for possible H1N1 2009 infection.
到2009年春季，人类感染H1N1病毒已达到大流行状态。因此，据报道，2009年H1N1感染相关的发病率和死亡率在孕妇中更高。H1N1病毒血症在母亲中很少见，2009年H1N1流感从母亲传播给胎儿的风险尚不清楚。据我们所知，文献中仅有一份先前的报告，是关于一名患有2009年H1N1感染的早产儿，其母亲也患有2009年H1N1感染。在此，我们报告一名妊娠32周出生的2009年H1N1大流行性流感阳性女早产儿，其母亲经实时逆转录聚合酶链反应（rRT-PCR）确诊感染2009年H1N1。该病例表明，2009年H1N1病毒可能通过胎盘传播，因此，必须对所有2009年H1N1阳性母亲所生的婴儿进行评估，以确定其是否可能感染2009年H1N1。
