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母乳喂养持续时间与台湾地区儿童发育迟缓风险的关系:一项全国性出生队列研究。

Duration of breast feeding and risk of developmental delay in Taiwanese children: a nationwide birth cohort study.

机构信息

School of Nutrition and Health Sciences, Taipei Medical University, Taiwan.

出版信息

Paediatr Perinat Epidemiol. 2011 Nov;25(6):519-27. doi: 10.1111/j.1365-3016.2011.01236.x. Epub 2011 Sep 15.

DOI:10.1111/j.1365-3016.2011.01236.x
PMID:21980941
Abstract

The purpose of this study was to examine the relationship between duration of breast feeding and four developmental domains: gross motor, fine motor, language, and personal/social skills. This study included 14,621 infants from birth to 18 months of age. In the Taiwan Birth Cohort Study, four developmental screening items adapted from the Denver Development Screening Test were most appropriate for children aged 15 to 18 months. The proportion of young children who had mastered specific milestones increased consistently with longer duration of breast feeding. The adjusted odds ratios of the risk of developmental delay for the longest duration of breast feeding vs. never breast-fed were 0.69 [95% confidence interval (CI) 0.57, 0.83] for gross motor, 0.64 [95% CI 0.53, 0.77] for fine motor, 0.74 [95% CI 0.60, 0.91] for language, and 0.76 [95% CI 0.64, 0.90] for personal/social skills. Regardless of when the mothers returned to work, duration of breast feeding was found to have an inverse association with developmental delay in young children. The protection against developmental delays remained significant for those children who were breast-fed for more than 6 months. Children who were breast-fed for longer than 6 months had a lower risk of developmental delay than those who were never breast-fed. These data support the hypothesis that duration of breast feeding is positively related to young children's neurodevelopment.

摘要

本研究旨在探讨母乳喂养持续时间与四个发育领域之间的关系

粗大运动、精细运动、语言和个人/社会技能。这项研究纳入了 14621 名 18 个月以下的婴儿。在台湾出生队列研究中,从 15 到 18 个月大的儿童最适合使用从丹佛发育筛查测试改编的四项发育筛查项目。掌握特定里程碑的幼儿比例随着母乳喂养时间的延长而持续增加。与从未母乳喂养的婴儿相比,母乳喂养时间最长的婴儿发育迟缓风险的调整比值比为 0.69(95%置信区间 0.57-0.83),粗大运动为 0.64(95%置信区间 0.53-0.77),精细运动为 0.74(95%置信区间 0.60-0.91),语言为 0.76(95%置信区间 0.64-0.90),个人/社会技能为 0.76(95%置信区间 0.64-0.90)。无论母亲何时返回工作岗位,母乳喂养时间与幼儿发育迟缓呈负相关。对于母乳喂养超过 6 个月的儿童,这种对发育迟缓的保护作用仍然显著。母乳喂养超过 6 个月的儿童发生发育迟缓的风险低于从未母乳喂养的儿童。这些数据支持母乳喂养时间与幼儿神经发育呈正相关的假设。

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