癌症患者化疗引起的恶心的治疗
Treatment of Chemotherapy-Induced Nausea in Cancer Patients.
作者信息
Ryan Julie L
机构信息
Departments of Dermatology and Radiation Oncology, University of Rochester Medical Center and James P. Wilmot Cancer Center, Rochester, NY.
出版信息
Eur Oncol. 2010;6(2):14-16. doi: 10.17925/eoh.2010.06.02.14.
Abstract
For over 30 years, chemotherapy-induced nausea and vomiting have been the most severe and troublesome symptoms for cancer patients receiving chemotherapy. Unresolved chemotherapy-induced nausea and vomiting can lead to metabolic disorders, dehydration, nutritional depletion and esophageal tears, and can reduce patients' daily functioning and quality of life and interfere with treatment schedules.(1, 2) Despite the widespread use of antiemetics, chemotherapy-induced nausea continues to be problematic. Unlike vomiting, nausea is a subjective and unobservable phenomenon making it extremely difficult to accurately assess and treat. Current research suggests that management of chemotherapy-induced nausea should focus on treating the symptoms before they occur rather than after they develop. This review highlights evidence-based interventions for the treatment of chemotherapy-related nausea.
摘要
30多年来，化疗引起的恶心和呕吐一直是接受化疗的癌症患者最严重、最棘手的症状。未解决的化疗引起的恶心和呕吐可导致代谢紊乱、脱水、营养耗竭和食管撕裂，并会降低患者的日常功能和生活质量，干扰治疗计划。（1,2）尽管止吐药被广泛使用，但化疗引起的恶心仍然是个问题。与呕吐不同，恶心是一种主观且无法观察到的现象，因此极难准确评估和治疗。目前的研究表明，化疗引起的恶心的管理应侧重于在症状出现之前而非出现之后进行治疗。本综述重点介绍了治疗化疗相关恶心的循证干预措施。
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