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本文引用的文献

1
Clinical research of Olanzapine for prevention of chemotherapy-induced nausea and vomiting.奥氮平预防化疗引起的恶心和呕吐的临床研究。
J Exp Clin Cancer Res. 2009 Sep 23;28(1):131. doi: 10.1186/1756-9966-28-131.
2
Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting.姜胶囊治疗化疗引起的恶心和呕吐的II期试验。
Support Care Cancer. 2009 May;17(5):563-72. doi: 10.1007/s00520-008-0528-8. Epub 2008 Nov 13.
3
A review of patient self-report tools for chemotherapy-induced nausea and vomiting.化疗引起的恶心和呕吐患者自我报告工具综述
Support Care Cancer. 2008 Nov;16(11):1213-29. doi: 10.1007/s00520-008-0428-y. Epub 2008 Jun 13.
4
Protein and ginger for the treatment of chemotherapy-induced delayed nausea.蛋白质和生姜用于治疗化疗引起的延迟性恶心。
J Altern Complement Med. 2008 Jun;14(5):545-51. doi: 10.1089/acm.2007.0817.
5
Review of acupressure studies for chemotherapy-induced nausea and vomiting control.用于控制化疗引起的恶心和呕吐的指压疗法研究综述。
J Pain Symptom Manage. 2008 Nov;36(5):529-44. doi: 10.1016/j.jpainsymman.2007.10.019. Epub 2008 Apr 28.
6
Antiemetics: an update and the MASCC guidelines applied in clinical practice.止吐药:最新进展及临床实践中应用的MASCC指南
Nat Clin Pract Oncol. 2008 Jan;5(1):32-43. doi: 10.1038/ncponc1021.
7
Anti-emetic therapy in cancer chemotherapy: current status.癌症化疗中的止吐治疗:现状
Basic Clin Pharmacol Toxicol. 2007 Sep;101(3):143-50. doi: 10.1111/j.1742-7843.2007.00122.x.
8
Chemotherapy-induced nausea and vomiting: clinician and patient perspectives.化疗引起的恶心和呕吐:临床医生与患者的观点
J Support Oncol. 2007 Feb;5(2 Suppl 1):5-12.
9
Behavioral interventions in treating anticipatory nausea and vomiting.治疗预期性恶心和呕吐的行为干预措施。
J Natl Compr Canc Netw. 2007 Jan;5(1):44-50. doi: 10.6004/jnccn.2007.0006.
10
The use of herbal therapies in pediatric oncology patients: treating symptoms of cancer and side effects of standard therapies.草药疗法在儿科肿瘤患者中的应用:治疗癌症症状及标准疗法的副作用。
J Pediatr Oncol Nurs. 2007 Jan-Feb;24(1):35-40. doi: 10.1177/1043454206296027.

癌症患者化疗引起的恶心的治疗

Treatment of Chemotherapy-Induced Nausea in Cancer Patients.

作者信息

Ryan Julie L

机构信息

Departments of Dermatology and Radiation Oncology, University of Rochester Medical Center and James P. Wilmot Cancer Center, Rochester, NY.

出版信息

Eur Oncol. 2010;6(2):14-16. doi: 10.17925/eoh.2010.06.02.14.

DOI:10.17925/eoh.2010.06.02.14
PMID:21984886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3188425/
Abstract

For over 30 years, chemotherapy-induced nausea and vomiting have been the most severe and troublesome symptoms for cancer patients receiving chemotherapy. Unresolved chemotherapy-induced nausea and vomiting can lead to metabolic disorders, dehydration, nutritional depletion and esophageal tears, and can reduce patients' daily functioning and quality of life and interfere with treatment schedules.(1, 2) Despite the widespread use of antiemetics, chemotherapy-induced nausea continues to be problematic. Unlike vomiting, nausea is a subjective and unobservable phenomenon making it extremely difficult to accurately assess and treat. Current research suggests that management of chemotherapy-induced nausea should focus on treating the symptoms before they occur rather than after they develop. This review highlights evidence-based interventions for the treatment of chemotherapy-related nausea.

摘要

30多年来,化疗引起的恶心和呕吐一直是接受化疗的癌症患者最严重、最棘手的症状。未解决的化疗引起的恶心和呕吐可导致代谢紊乱、脱水、营养耗竭和食管撕裂,并会降低患者的日常功能和生活质量,干扰治疗计划。(1,2)尽管止吐药被广泛使用,但化疗引起的恶心仍然是个问题。与呕吐不同,恶心是一种主观且无法观察到的现象,因此极难准确评估和治疗。目前的研究表明,化疗引起的恶心的管理应侧重于在症状出现之前而非出现之后进行治疗。本综述重点介绍了治疗化疗相关恶心的循证干预措施。