具有范式转移意义的疫苗：针对潜伏性水痘-带状疱疹病毒感染和 HPV 相关癌症的预防性疫苗。
Paradigm shifting vaccines: prophylactic vaccines against latent varicella-zoster virus infection and against HPV-associated cancer.
机构信息
Translational Research Institute, The University of Queensland Diamantina Institute, PO Box 6116, Buranda Queensland 4102, Australia.
出版信息
Curr Opin Virol. 2011 Oct;1(4):268-79. doi: 10.1016/j.coviro.2011.07.007.
Abstract
We compare the design, mechanism of action, and clinical efficacy of two recently licensed paradigm shifting vaccines. Zostavax is the first vaccine licensed to prevent disease in patients already infected with a pathogen, and is contrasted with Gardasil and Cervarix, the first vaccines designed and licensed specifically to prevent cancers.
摘要
我们比较了两种最近获得许可的具有开创性的疫苗的设计、作用机制和临床疗效。Zostavax 是第一种获准用于预防已感染病原体的患者疾病的疫苗，与之形成对比的是 Gardasil 和 Cervarix，这两种疫苗是专门为预防癌症而设计和许可的第一种疫苗。
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