Emergency and Critical Care Medical Center, Osaka Police Hospital, 10-31 Kitayama-cho Tennouji-ku, Osaka 543-0035, Japan.
Crit Care. 2011;15(5):R236. doi: 10.1186/cc10483. Epub 2011 Oct 10.
Both supraglottic airway devices (SGA) and endotracheal intubation (ETI) have been used by emergency life-saving technicians (ELST) in Japan to treat out-of-hospital cardiac arrests (OHCAs). Despite traditional emphasis on airway management during cardiac arrest, its impact on survival from OHCA and time dependent effectiveness remains unclear.
All adults with witnessed, non-traumatic OHCA, from 1 January 2005 to 31 December 2008, treated by the emergency medical services (EMS) with an advanced airway in Osaka, Japan were studied in a prospective Utstein-style population cohort database. The primary outcome measure was one-month survival with neurologically favorable outcome. The association between type of advanced airway (ETI/SGA), timing of device placement and neurological outcome was assessed by multiple logistic regression.
Of 7,517 witnessed non-traumatic OHCAs, 5,377 cases were treated with advanced airways. Of these, 1,679 were ETI while 3,698 were SGA. Favorable neurological outcome was similar between ETI and SGA (3.6% versus 3.6%, P = 0.95). The time interval from collapse to ETI placement was significantly longer than for SGA (17.2 minutes versus 15.8 minutes, P < 0.001). From multivariate analysis, early placement of an advanced airway was significantly associated with better neurological outcome (Adjusted Odds Ratio (AOR) for one minute delay, 0.91, 95% confidence interval (CI) 0.88 to 0.95). ETI was not a significant predictor (AOR 0.71, 95% CI 0.39 to 1.30) but the presence of an ETI certified ELST (AOR, 1.86, 95% CI 1.04 to 3.34) was a significant predictor for favorable neurological outcome.
There was no difference in neurologically favorable outcome from witnessed OHCA for ETI versus SGA. Early airway management with advanced airway regardless of type and rhythm was associated with improved outcomes.
在日本,紧急救生技术员(ELST)在治疗院外心脏骤停(OHCA)时,既使用了声门上气道装置(SGA),也使用了气管内插管(ETI)。尽管传统上强调心脏骤停期间的气道管理,但它对 OHCA 患者生存率和时间相关有效性的影响仍不清楚。
本研究采用前瞻性乌斯丁式人群队列数据库,对 2005 年 1 月 1 日至 2008 年 12 月 31 日期间在日本大阪由急救医疗服务(EMS)治疗的目击、非创伤性 OHCA 的所有成年人进行研究。主要结局测量指标为 1 个月时具有神经功能良好结局的生存情况。通过多变量逻辑回归评估高级气道(ETI/SGA)类型、设备放置时间与神经结局之间的关系。
在 7517 例目击非创伤性 OHCA 中,5377 例采用了高级气道治疗。其中,1679 例为 ETI,3698 例为 SGA。ETI 和 SGA 的神经功能良好结局相似(3.6%比 3.6%,P=0.95)。从心脏骤停到 ETI 放置的时间间隔明显长于 SGA(17.2 分钟比 15.8 分钟,P<0.001)。多变量分析显示,早期放置高级气道与更好的神经结局显著相关(每延迟 1 分钟的校正优势比(AOR)为 0.91,95%置信区间(CI)为 0.88 至 0.95)。ETI 不是一个显著的预测因素(AOR 为 0.71,95%CI 为 0.39 至 1.30),但有 ETI 认证的 ELST(AOR 为 1.86,95%CI 为 1.04 至 3.34)是神经功能良好结局的显著预测因素。
在有目击者的 OHCA 中,ETI 与 SGA 的神经功能良好结局没有差异。无论类型和节律如何,早期进行高级气道管理均与改善结局相关。