Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo (SP), Brazil.
Epilepsy Behav. 2011 Dec;22(4):718-22. doi: 10.1016/j.yebeh.2011.08.033. Epub 2011 Oct 8.
Although the available evidence suggests that exercise may positively affect epilepsy, whether this effect is applicable to different types of epilepsy has not been established. Physiological responses during rest, acute physical effort, and a recovery period were studied by concomitant analysis of cerebral electric activity using EEGs in subjects with juvenile myoclonic epilepsy (JME) and healthy controls. In addition, level of habitual physical activity, body composition, and 1 week of actigraphy monitoring data were evaluated. Twenty-four subjects (12 with JME and 12 controls) participated in this study. Compared with the control group, the JME group had a significantly lower V˙O(2) at rest (13.3%) and resting metabolic rate (15.6%). The number of epileptiform discharges in the JME group was significantly reduced during the recovery period (72%) compared with the resting state. There were no significant differences between the JME and control groups in behavioral outcomes and sleep parameters evaluated by actigraphy monitoring. The positive findings of our study strengthen the evidence for the benefits of physical exercise for people with JME.
尽管现有证据表明运动可能对癫痫产生积极影响，但这种影响是否适用于不同类型的癫痫尚未确定。通过同时分析青少年肌阵挛性癫痫（JME）患者和健康对照组的脑电图，研究了静息、急性体力活动和恢复期的生理反应。此外，还评估了习惯性体力活动水平、身体成分和 1 周的活动监测数据。24 名受试者（12 名 JME 和 12 名对照组）参加了这项研究。与对照组相比，JME 组在静息时（13.3%）和静息代谢率（15.6%）显著降低。与静息状态相比，JME 组在恢复期癫痫样放电的数量显著减少（72%）。通过活动监测评估行为结果和睡眠参数，JME 组和对照组之间没有显著差异。我们的研究的积极发现加强了运动对 JME 患者有益的证据。
