Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
J Appl Oral Sci. 2011 Oct;19(5):448-54. doi: 10.1590/s1678-77572011000500003.
Radiotherapy, alone or associated with surgery or chemotherapy, produces a significant increase in cure rates for many malignancies of the head and neck region. However, high doses of radiation in large areas, including the oral mucosa, may result in several undesired reactions that manifest during or after the completion of therapy. The multidisciplinary management is the best alternative to minimize or even prevent such reactions, and the dentist has a fundamental role in this context. This paper reviews the literature related to the main oral sequelae from head and neck radiotherapy and establishes clinical oral management protocol for these irradiated patients.
放疗单独或联合手术或化疗可显著提高头颈部多种恶性肿瘤的治愈率。然而，大剂量照射口腔黏膜等大面积区域可能导致治疗期间或治疗后出现多种不良反应。多学科管理是最大限度减少甚至预防这些不良反应的最佳选择，牙医在这方面发挥着重要作用。本文复习了与头颈部放疗后主要口腔后遗症相关的文献，并为这些接受放疗的患者制定了临床口腔管理方案。
