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声门上成形术失败的危险因素。

Risk factors for supraglottoplasty failure.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.

出版信息

Otolaryngol Head Neck Surg. 2012 Feb;146(2):298-301. doi: 10.1177/0194599811425652. Epub 2011 Oct 10.

Abstract

OBJECTIVE

To review outcomes after supraglottoplasty for laryngomalacia and identify risk factors for supraglottoplasty failure.

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary care children's hospital.

SUBJECTS AND METHODS

Retrospective case series evaluating patient outcomes after supraglottoplasty at an academic medical center between 2004 and 2010. Surgical failure was defined as need for revision surgery, tracheostomy tube placement, or gastrostomy tube insertion. Multivariable logistic regression was performed to identify risk factors for failure.

RESULTS

The authors identified 95 children who underwent supraglottoplasty. After excluding patients with inadequate follow-up data, 74 patients were included. On the basis of chart review, 12 (16%) of those patients were defined as failures according to the criteria above. Age, history of prematurity (<34 weeks' gestational age), weight, growth curve percentile, neurologic/developmental problems, genetic syndrome, cardiac abnormality, synchronous airway lesions, and surgical technique were considered in risk factor analysis. Multivariable logistic regression was performed, revealing history of prematurity to be the only independent risk factor for failure (odds ratio = 4.85; 95% confidence interval, 1.07-22.1; P = .041).

CONCLUSIONS

Outcomes after supraglottoplasty were comparable to previous reports in the literature. History of prematurity should be considered a risk factor for surgical failure.

摘要

目的

回顾声门上成形术治疗喉软化症的结果,并确定声门上成形术失败的风险因素。

研究设计

病例系列和图表回顾。

设置

三级儿童保健医院。

受试者和方法

回顾性病例系列评估 2004 年至 2010 年在学术医疗中心行声门上成形术的患者结局。手术失败定义为需要再次手术、气管造口术置管或胃造口术置管。采用多变量逻辑回归确定失败的风险因素。

结果

作者共确定了 95 例行声门上成形术的儿童。在排除随访数据不充分的患者后,纳入 74 例患者。根据图表回顾,根据上述标准,有 12 例(16%)患者被定义为失败。考虑到年龄、早产史(<34 周胎龄)、体重、生长曲线百分位数、神经/发育问题、遗传综合征、心脏异常、同期气道病变和手术技术等因素,进行了风险因素分析。进行多变量逻辑回归,结果显示早产史是失败的唯一独立风险因素(比值比=4.85;95%置信区间,1.07-22.1;P=0.041)。

结论

声门上成形术的结果与文献中的既往报道相似。早产史应被视为手术失败的风险因素。

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本文引用的文献

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Supraglottoplasty outcomes in relation to age and comorbid conditions.声门上成形术的结果与年龄和合并症的关系。
Int J Pediatr Otorhinolaryngol. 2010 Mar;74(3):245-9. doi: 10.1016/j.ijporl.2009.11.012. Epub 2009 Dec 21.
4
Objective assessment of supraglottoplasty outcomes using polysomnography.使用多导睡眠图对声门上成形术结果进行客观评估。
Int J Pediatr Otorhinolaryngol. 2009 Sep;73(9):1211-6. doi: 10.1016/j.ijporl.2009.05.007. Epub 2009 Jun 12.
8
[Treatment laryngomalacia: experience with 22 cases].[喉软化症的治疗:22例经验]
Braz J Otorhinolaryngol. 2005 May-Jun;71(3):330-4. doi: 10.1016/s1808-8694(15)31331-8. Epub 2005 Dec 14.
9
Humans are born too soon: impact on pediatric otolaryngology.人类过早出生:对小儿耳鼻喉科的影响。
Int J Pediatr Otorhinolaryngol. 2005 Jan;69(1):1-8. doi: 10.1016/j.ijporl.2004.07.021.

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