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[伴有和不伴有神经功能障碍的重度喉软化症患儿的内镜下声门上成形术]

[Endoscopic supraglottoplasty in children with severe laryngomalacia with and without neurological impairment].

作者信息

Fraga J C, Schopf L, Volker V, Canani S

机构信息

Hospital de Clínicas (HCPA), Porto Alegre, RS, Brazil.

出版信息

J Pediatr (Rio J). 2001 Sep-Oct;77(5):420-4. doi: 10.2223/jped.285.

Abstract

OBJECTIVE

To describe indications and results of supraglottoplasty for severe laryngomalacia in children with or without neurological impairment. METHODS: Eight children with severe laryngomalacia submitted to endoscopic supraglottoplasty were retrospectively studied. Four had neurological impairment (male, mean age 6 years), and 4 did not present neurological problems (3 female, mean age 11.5 months). Surgery indications were respiratory distress, feeding difficulties, failure to thrive, and low oxygen saturation. Polysomnographic evaluation was carried out on the last 2 children, showing abnormal oxygen saturation, obstructive apnea, and hypoventilation. All children received preoperative antibiotics and corticosteroids. RESULTS: All children without neurological impairment had significant relief of symptoms. Children with neurological impairment had different outcome: one needed tracheotomy immediately after surgery due to edema and supraglottic granulation tissue. The other three children presented initial relief of symptoms, but subsequent follow-up showed progressive airway obstruction: one needed another endoscopic surgery 6 months later; other needed tracheotomy 7 months later. The children who were not submitted to tracheostomy presented persistent severe airway obstruction. No endoscopic surgery complication was observed. CONCLUSIONS: 1) Endoscopic supraglottoplasty is well tolerated and does not present complications when used in children; 2) Endoscopic supraglottoplasty was efficient in the treatment of children with severe laryngomalacia and in without neurological impairment; however, supraglottoplasty did not resolve airway obstruction in children with neurological impairment.

摘要

目的

描述伴有或不伴有神经功能障碍的儿童严重喉软化症声门上成形术的适应证及结果。方法:回顾性研究8例接受内镜声门上成形术的严重喉软化症患儿。4例有神经功能障碍(男性,平均年龄6岁),4例无神经问题(3例女性,平均年龄11.5个月)。手术适应证为呼吸窘迫、喂养困难、生长发育迟缓及低氧饱和度。对最后2例患儿进行了多导睡眠图评估,显示氧饱和度异常、阻塞性呼吸暂停和通气不足。所有患儿术前均接受抗生素和皮质类固醇治疗。结果:所有无神经功能障碍的患儿症状均有明显缓解。有神经功能障碍的患儿结果不同:1例术后因水肿和声门上肉芽组织立即需要气管切开术。另外3例患儿最初症状缓解,但随后的随访显示气道阻塞逐渐加重:1例6个月后需要再次内镜手术;另1例7个月后需要气管切开术。未接受气管切开术的患儿存在持续性严重气道阻塞。未观察到内镜手术并发症。结论:1)内镜声门上成形术在儿童中耐受性良好,且无并发症;2)内镜声门上成形术对治疗严重喉软化症且无神经功能障碍的儿童有效;然而,声门上成形术不能解决有神经功能障碍儿童的气道阻塞问题。

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