Centre for Infection and Immunity, Queens University Belfast, Belfast, Northern Ireland.
Semin Respir Crit Care Med. 2011 Oct;32(5):607-25. doi: 10.1055/s-0031-1287870. Epub 2011 Oct 11.
Lung failure is the most common organ failure seen in the intensive care unit. The pathogenesis of acute respiratory failure (ARF) can be classified as (1) neuromuscular in origin, (2) secondary to acute and chronic obstructive airway diseases, (3) alveolar processes such as cardiogenic and noncardiogenic pulmonary edema and pneumonia, and (4) vascular diseases such as acute or chronic pulmonary embolism. This article reviews the more common causes of ARF from each group, including the pathological mechanisms and the principles of critical care management, focusing on the supportive, specific, and adjunctive therapies for each condition.
肺衰竭是重症监护病房最常见的器官衰竭。急性呼吸衰竭(ARF)的发病机制可分为(1)神经肌肉源性,(2)继发于急性和慢性阻塞性气道疾病,(3)肺泡过程,如心源性和非心源性肺水肿和肺炎,以及(4)血管疾病,如急性或慢性肺栓塞。本文从每组中回顾 ARF 的更常见原因,包括病理机制和重症监护管理原则,重点介绍每种情况的支持、特定和辅助治疗。