Lazovic G, Colic M, Grubor M, Jovanovic M
Centre for Burns, Plastic, and Reconstructive Surgery, Clinical Centre of Serbia, Belgrade, Serbia and Montenegro.
Ann Burns Fire Disasters. 2005 Sep 30;18(3):151-6.
The aim of this paper is describe the application of desamidated collagen as a biomaterial in order to evaluate the utility of collagen, particularly as a drug delivery device, as a haemostat, and as a wound cover. We also evaluated the utility of vitamin A, vitamin C, 50% glucose, and gentamicin locally applied onto the open wound. Any biomaterial should ensure non-toxicity to the biological environment where it is applied. We point out the utility of vitamin A, vitamin C, 50% glucose, and gentamicin locally applied onto the open wound with a biological covering. Collagen sheet is becoming evident in our ongoing studies. We are convinced that collagen sheets are very useful in first- and second-degree burns. The cost factor comes down and the pain associated with dressing can be avoided. Especially in children it is very useful since the trauma of dressing can be avoided.
本文旨在描述脱酰胺胶原蛋白作为生物材料的应用，以评估胶原蛋白的效用，特别是作为药物递送装置、止血剂和伤口覆盖物的效用。我们还评估了局部应用于开放性伤口的维生素A、维生素C、50%葡萄糖和庆大霉素的效用。任何生物材料都应确保对其应用的生物环境无毒。我们指出了局部应用于有生物覆盖物的开放性伤口的维生素A、维生素C、50%葡萄糖和庆大霉素的效用。在我们正在进行的研究中，胶原片的效用正变得明显。我们相信胶原片在一度和二度烧伤中非常有用。成本因素降低，并且可以避免与换药相关的疼痛。特别是对儿童来说非常有用，因为可以避免换药的创伤。
