胶原基质膜作为口腔黏膜缺损的生物敷料
Collagen matrix membrane as a biological dressing in defects of the oral mucosa.
作者信息
Ahmad Fahad, Lata Jeevan
机构信息
Department of Oral and Maxillofacial Surgery, Al-Jahra Specialty Dental Center, Al-Jahra, Kuwait.
Department of Oral and Maxillofacial Surgery, Punjab Government Dental College and Hospital, Amritsar, Punjab, India.
出版信息
Natl J Maxillofac Surg. 2021 May-Aug;12(2):199-205. doi: 10.4103/njms.NJMS_128_20. Epub 2021 Jul 15.
OBJECTIVES
The objectives of this study were to evaluate the usefulness of the extracellular collagen matrix membrane as a biological wound dressing material for defects of the oral mucosa.
MATERIALS AND METHODS
One hundred two patients were included in the study. A bovine-based extracellular matrix collagen membrane was used. The study was confined to those defects of oral mucosa which were large enough to close primarily.
RESULTS
The results were evaluated under various parameters such as hemostasis, pain relief, granulation, epithelialization, and contracture of the wound. Secondary infection and allergenicity to the membrane were also considered, and finally, the usefulness of the collagen membrane was tested by the use of the Chi-square test and < 0.001 was found.
CONCLUSION
We concluded that the extracellular collagen membrane could be used as a biological dressing in oral defects. Although it does not replace, it is proved as a good substitute of autologous graft.
目的
本研究的目的是评估细胞外胶原基质膜作为口腔黏膜缺损生物伤口敷料材料的实用性。
材料与方法
102名患者纳入本研究。使用了一种基于牛的细胞外基质胶原膜。该研究仅限于那些大到足以直接缝合的口腔黏膜缺损。
结果
在诸如止血、疼痛缓解、肉芽形成、上皮化和伤口挛缩等各种参数下对结果进行评估。还考虑了对该膜的继发感染和致敏性，最后，通过卡方检验测试胶原膜的实用性，发现P<0.001。
结论
我们得出结论，细胞外胶原膜可用于口腔缺损的生物敷料。虽然它不能替代自体移植，但被证明是自体移植的良好替代品。
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