Sín P, Stupka I, Brychta P
Department of Burns and Reconstructive Surgery, Brno University Hospital, Brno, Czech Republic.
Ann Burns Fire Disasters. 2010 Dec 31;23(4):208-13.
In our preliminary experiments we found that composite skin grafts consisting of allogeneic acellular dermis and thin epidermal autologous grafts applied to the excised burn wound in one stage led to better results in terms of viscoelastic properties than autologous split-thickness skin grafts.
In ten burn patients we applied composite skin grafts consisting of allogeneic acellular dermis and thin epidermal autologous grafts and followed the quality of the reconstructed skin cover with a special device, Cutometer MPA 580, over a period of four years.
The cutometric curves demonstrated better viscoelastic properties in composite skin grafts than in conventional split-thickness skin grafts after four years. We found Cutometer MPA 580 to be an advantageous device for the objectification of improved quality of reconstructed skin cover.
Among the various methods the cutometer showed the advantage of being a non-invasive, precise, and objective method of measuring skin's viscoelastic properties. The Vancouver Scar Score is a subjective evaluation of skin viscoelasticity.
Our prospective clinical study clearly demonstrated that cutometric measurement produced objective results in contrast to clinical evaluation, the Vancouver Scar Score, and other non-quantitative methods. Our hypothesis that composite skin grafts consisting of allogeneic acellular dermis and thin epidermal autologous grafts applied onto the excised burn wound in one stage led to better results in terms of viscoelastic properties than autologous split-thickness skin grafts was fully confirmed.
在我们的初步实验中,我们发现,将由同种异体脱细胞真皮和自体薄表皮移植物组成的复合皮肤移植物一次性应用于切除的烧伤创面,在粘弹性方面比自体中厚皮片产生更好的效果。
在10名烧伤患者中,我们应用了由同种异体脱细胞真皮和自体薄表皮移植物组成的复合皮肤移植物,并使用一种特殊设备Cutometer MPA 580对重建皮肤覆盖物的质量进行了为期四年的跟踪。
四年后,皮肤弹性测定曲线显示复合皮肤移植物的粘弹性比传统中厚皮片更好。我们发现Cutometer MPA 580是一种用于客观评估重建皮肤覆盖物质量改善的有利设备。
在各种方法中,皮肤弹性测定仪显示出其作为一种测量皮肤粘弹性的非侵入性、精确且客观的方法的优势。温哥华瘢痕评分是对皮肤粘弹性的主观评估。
我们的前瞻性临床研究清楚地表明,与临床评估、温哥华瘢痕评分及其他非定量方法相比,皮肤弹性测定测量产生了客观结果。我们的假设,即一次性将由同种异体脱细胞真皮和自体薄表皮移植物组成的复合皮肤移植物应用于切除的烧伤创面,在粘弹性方面比自体中厚皮片产生更好的效果,得到了充分证实。