Salma Umme, Gill Harjinder Kaur, Keith Louis G, Tilmon Sandra, Jones Christopher A, Sobti Anjali, Patel Ashlesha
The Sims Institute/Sims IVF; Dublin, IRELAND.
J Exp Clin Assist Reprod. 2011;8:1. Epub 2011 Aug 9.
The concept of male subfertility has evolved rapidly since 2000. This term is discussed based upon evidence relating to its first entrance into the literature, along with contemporary references to its purported incidence and prevalence. Factors affecting sperm quality are described in detail, and available data pertaining to the effects of micronutrients on spermatic parameters and resulting pregnancies are described. The first cost-efficiency analysis of the use of micronutrients vs. assisted reproductive technologies is presented. This paper also describes a therapeutic approach to males, recognizing that many potential fathers have no recourse to medical facilities to evaluate their fertility. At a time when medical dollars are either nonexistent or precious, such an approach using micronutrient supplementation may be cost-effective in developing and possibly even in developed countries.
自2000年以来，男性生育力低下的概念发展迅速。本文将根据该术语首次出现在文献中的相关证据进行讨论，并提及有关其所谓发病率和患病率的当代参考文献。详细描述了影响精子质量的因素，以及有关微量营养素对精子参数和妊娠结局影响的现有数据。首次提出了使用微量营养素与辅助生殖技术的成本效益分析。本文还描述了一种针对男性的治疗方法，因为认识到许多准父亲无法借助医疗设施来评估自己的生育能力。在医疗资金匮乏或宝贵的时代，这种使用微量营养素补充剂的方法在发展中国家甚至可能在发达国家可能具有成本效益。
