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The effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial.玫瑰茄对血脂、肌酐和血清电解质的影响:一项随机临床试验。
ISRN Gastroenterol. 2011;2011:976019. doi: 10.5402/2011/976019. Epub 2010 Nov 7.
2
Effects of Hibiscus sabdariffa L. on serum lipids: a systematic review and meta-analysis.荷叶对血清脂质的影响:系统评价和荟萃分析。
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Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy).荷叶提取物粉末及预防治疗(饮食)对代谢综合征(MeSy)患者血脂谱的影响。
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Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies.鸡冠花(Hibiscus sabdariffa L.)在治疗高血压和高血脂症方面的应用:动物和人体研究的综合综述。
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Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes.酸茶(玫瑰茄)对II型糖尿病患者血脂谱和脂蛋白的影响。
J Altern Complement Med. 2009 Aug;15(8):899-903. doi: 10.1089/acm.2008.0540.
6
Efficacy of standardized extract of Hibiscus sabdariffa L. (Malvaceae) in improving iron status of adults in malaria endemic area: A randomized controlled trial.规范化鸡冠花(锦葵科)提取物改善疟疾流行区成年人铁状况的功效:一项随机对照试验。
J Ethnopharmacol. 2017 Sep 14;209:288-293. doi: 10.1016/j.jep.2017.07.037. Epub 2017 Jul 26.
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The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta-analysis of randomized clinical trials.酸茶(洛神花)对部分心血管疾病风险因素的功效:随机临床试验的系统评价和荟萃分析。
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Effect of Hibiscus sabdariffa Calices on Dyslipidemia in Obese Adolescents: A Triple-masked Randomized Controlled Trial.玫瑰茄萼片对肥胖青少年血脂异常的影响:一项三盲随机对照试验。
Mater Sociomed. 2013;25(2):76-9. doi: 10.5455/msm.2013.25.76-79.
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The consumption of Hibiscus sabdariffa dried calyx ethanolic extract reduced lipid profile in rats.玫瑰茄干萼片乙醇提取物的摄入降低了大鼠的血脂水平。
Plant Foods Hum Nutr. 2005 Dec;60(4):153-9. doi: 10.1007/s11130-005-9023-x.
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Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial.一种标准化木槿属药用产品对高血压患者的临床疗效。一项随机、双盲、赖诺普利对照的临床试验。
Planta Med. 2007 Jan;73(1):6-12. doi: 10.1055/s-2006-957065.

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Exploring the Health Benefits and Therapeutic Potential of Roselle (Hibiscus sabdariffa) in Human Studies: A Comprehensive Review.探索玫瑰茄(木槿属)在人体研究中的健康益处和治疗潜力:一项综合综述。
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Hibiscus sabdariffa extract improves hepatic steatosis, partially through IRS-1/Akt and Nrf2 signaling pathways in rats fed a high fat diet.玫瑰茄提取物可改善高脂肪饮食喂养大鼠的肝脂肪变性,部分通过 IRS-1/Akt 和 Nrf2 信号通路。
Sci Rep. 2022 Apr 29;12(1):7022. doi: 10.1038/s41598-022-11027-9.
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Physiological Effects and Human Health Benefits of : A Review of Clinical Trials.《[具体内容]的生理效应及对人类健康的益处:临床试验综述》 (因原文冒号前内容缺失,只能给出大概形式,需补充完整原文冒号前内容才能准确翻译)
Pharmaceuticals (Basel). 2022 Apr 12;15(4):464. doi: 10.3390/ph15040464.
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A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers.系统评价和荟萃分析小豆蔻红对血压和心脏代谢标志物的影响。
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The effects of adding L. flowers marmalade on some quality properties, mineral content and antioxidant activities of yogurt.添加洛神花果酱对酸奶某些品质特性、矿物质含量及抗氧化活性的影响。
J Food Sci Technol. 2021 Jan;58(1):223-233. doi: 10.1007/s13197-020-04533-z. Epub 2020 May 24.
6
Effects of aqueous extracts of dried calyx of sour tea ( L.) on polygenic dyslipidemia: A randomized clinical trial.酸茶(L.)干燥花萼水提取物对多基因血脂异常的影响:一项随机临床试验。
Avicenna J Phytomed. 2018 Jan-Feb;8(1):24-32.
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The Effect of Green Tea versus Sour Tea on Insulin Resistance, Lipids Profiles and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial.绿茶与酸茶对2型糖尿病患者胰岛素抵抗、血脂谱及氧化应激的影响:一项随机临床试验
Iran J Med Sci. 2014 Sep;39(5):424-32.
8
Anthocyanin - Rich Red Dye of Hibiscus Sabdariffa Calyx Modulates Cisplatin-induced Nephrotoxicity and Oxidative Stress in Rats.玫瑰茄萼片中富含花青素的红色染料对顺铂诱导的大鼠肾毒性和氧化应激的调节作用
Int J Biomed Sci. 2013 Dec;9(4):243-8.
9
Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies.鸡冠花(Hibiscus sabdariffa L.)在治疗高血压和高血脂症方面的应用:动物和人体研究的综合综述。
Fitoterapia. 2013 Mar;85:84-94. doi: 10.1016/j.fitote.2013.01.003. Epub 2013 Jan 17.

本文引用的文献

1
Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial.玫瑰茄标准化提取物对轻至中度高血压患者的有效性和耐受性:一项对照随机临床试验。
Phytomedicine. 2004 Jul;11(5):375-82. doi: 10.1016/j.phymed.2004.04.001.
2
Herbal medicine in Jordan with special emphasis on commonly used herbs.约旦的草药医学,特别强调常用草药。
J Ethnopharmacol. 2003 Dec;89(2-3):193-7. doi: 10.1016/s0378-8741(03)00283-6.
3
In vitro analysis of the properties of Beiqishen tea.
Nutrition. 2003 Oct;19(10):869-75. doi: 10.1016/s0899-9007(03)00157-6.
4
Toxicological investigation of aqueous-methanolic extract of the calyces of Hibiscus sabdariffa L.玫瑰茄花萼水甲醇提取物的毒理学研究
J Ethnopharmacol. 2003 Nov;89(1):161-4. doi: 10.1016/s0378-8741(03)00276-9.
5
Hibiscus sabdariffa extract inhibits the development of atherosclerosis in cholesterol-fed rabbits.玫瑰茄提取物可抑制喂饲胆固醇的家兔动脉粥样硬化的发展。
J Agric Food Chem. 2003 Aug 27;51(18):5472-7. doi: 10.1021/jf030065w.
6
Chronic administration of aqueous extract of Hibiscus sabdariffa attenuates hypertension and reverses cardiac hypertrophy in 2K-1C hypertensive rats.长期给予玫瑰茄水提取物可减轻2K-1C高血压大鼠的高血压并逆转心脏肥大。
J Ethnopharmacol. 2003 Jun;86(2-3):181-5. doi: 10.1016/s0378-8741(03)00078-3.
7
Protective effect of Hibiscus anthocyanins against tert-butyl hydroperoxide-induced hepatic toxicity in rats.木槿花青素对叔丁基过氧化氢诱导的大鼠肝毒性的保护作用。
Food Chem Toxicol. 2000 May;38(5):411-6. doi: 10.1016/s0278-6915(00)00011-9.
8
Mechanisms of the blood pressure lowering effect of the calyx extract of Hibiscus sabdariffa in rats.玫瑰茄花萼提取物对大鼠的降压作用机制
Afr J Med Med Sci. 1996 Sep;25(3):235-8.
9
Antihypertensive effect of roselle (Hibiscus sabdariffa) calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in Wistar rats.玫瑰茄(Hibiscus sabdariffa)萼片浸剂对自发性高血压大鼠的降压作用及其与Wistar大鼠毒性的比较。
Cell Biochem Funct. 1999 Sep;17(3):199-206. doi: 10.1002/(SICI)1099-0844(199909)17:3<199::AID-CBF829>3.0.CO;2-2.
10
The effect of sour tea (Hibiscus sabdariffa) on essential hypertension.酸茶(玫瑰茄)对原发性高血压的影响。
J Ethnopharmacol. 1999 Jun;65(3):231-6. doi: 10.1016/s0378-8741(98)00157-3.

玫瑰茄对血脂、肌酐和血清电解质的影响:一项随机临床试验。

The effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial.

作者信息

Mohagheghi Abbas, Maghsoud Shirin, Khashayar Patricia, Ghazi-Khansari Mohammad

机构信息

Department of Cardiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran 14114, Iran.

出版信息

ISRN Gastroenterol. 2011;2011:976019. doi: 10.5402/2011/976019. Epub 2010 Nov 7.

DOI:10.5402/2011/976019
PMID:21991538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3168576/
Abstract

Background. Hibiscus Sabdariffa L. (HS), a member of malvaceae family, is a medicinal plant with a worldwide fame. Its effect on reducing serum lipids is mentioned in several studies. The purpose of this study was to assess the efficacy of this plant in reducing the serum's lipids in hypertensive patients. Materials and Methods. Ninety hypertensive patients were randomly assigned to receive Hibiscus Sabdariffa (HS) tea or black tea for 15 days. The patients were asked to drink the tea within 20 minutes following its preparation. This process had to be repeated two times, daily. Patient's FBS and lipid profile were collected at the first visit day (day 0) and on the day 30. Results. There was no significant differences between pre and post experiment values within the two groups. An upward trend in total cholesterol, HDL, and LDL cholesterol was evident in both groups. The increase in total and HDL cholesterol in both groups relative to their initial values were significant. Conclusion. Hibiscus Sabdariffa is probably a safe medicinal plant. No significant harmful changes in cholesterol, triglyceride, BUN, serum creatinine, Na and K levels were observed within 15 days after the discontinuation of the medication.

摘要

背景。玫瑰茄(Hibiscus Sabdariffa L.,HS)是锦葵科植物,是一种闻名全球的药用植物。多项研究提到了其降血脂作用。本研究旨在评估该植物对高血压患者降血脂的疗效。材料与方法。90例高血压患者被随机分配接受玫瑰茄(HS)茶或红茶,为期15天。要求患者在茶泡好后20分钟内饮用。此过程每天重复两次。在首次就诊日(第0天)和第30天收集患者的空腹血糖(FBS)和血脂谱。结果。两组实验前后的值无显著差异。两组的总胆固醇、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)胆固醇均呈上升趋势。两组总胆固醇和HDL胆固醇相对于初始值的增加具有显著性。结论。玫瑰茄可能是一种安全的药用植物。停药后15天内,未观察到胆固醇、甘油三酯、血尿素氮(BUN)、血清肌酐、钠和钾水平有显著有害变化。