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玫瑰茄对血脂、肌酐和血清电解质的影响:一项随机临床试验。

The effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial.

作者信息

Mohagheghi Abbas, Maghsoud Shirin, Khashayar Patricia, Ghazi-Khansari Mohammad

机构信息

Department of Cardiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran 14114, Iran.

出版信息

ISRN Gastroenterol. 2011;2011:976019. doi: 10.5402/2011/976019. Epub 2010 Nov 7.

Abstract

Background. Hibiscus Sabdariffa L. (HS), a member of malvaceae family, is a medicinal plant with a worldwide fame. Its effect on reducing serum lipids is mentioned in several studies. The purpose of this study was to assess the efficacy of this plant in reducing the serum's lipids in hypertensive patients. Materials and Methods. Ninety hypertensive patients were randomly assigned to receive Hibiscus Sabdariffa (HS) tea or black tea for 15 days. The patients were asked to drink the tea within 20 minutes following its preparation. This process had to be repeated two times, daily. Patient's FBS and lipid profile were collected at the first visit day (day 0) and on the day 30. Results. There was no significant differences between pre and post experiment values within the two groups. An upward trend in total cholesterol, HDL, and LDL cholesterol was evident in both groups. The increase in total and HDL cholesterol in both groups relative to their initial values were significant. Conclusion. Hibiscus Sabdariffa is probably a safe medicinal plant. No significant harmful changes in cholesterol, triglyceride, BUN, serum creatinine, Na and K levels were observed within 15 days after the discontinuation of the medication.

摘要

背景。玫瑰茄(Hibiscus Sabdariffa L.,HS)是锦葵科植物,是一种闻名全球的药用植物。多项研究提到了其降血脂作用。本研究旨在评估该植物对高血压患者降血脂的疗效。材料与方法。90例高血压患者被随机分配接受玫瑰茄(HS)茶或红茶,为期15天。要求患者在茶泡好后20分钟内饮用。此过程每天重复两次。在首次就诊日(第0天)和第30天收集患者的空腹血糖(FBS)和血脂谱。结果。两组实验前后的值无显著差异。两组的总胆固醇、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)胆固醇均呈上升趋势。两组总胆固醇和HDL胆固醇相对于初始值的增加具有显著性。结论。玫瑰茄可能是一种安全的药用植物。停药后15天内,未观察到胆固醇、甘油三酯、血尿素氮(BUN)、血清肌酐、钠和钾水平有显著有害变化。

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