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经皮内窥镜腰椎间盘切除术和环锯成形术治疗腰椎间盘突出症后腰痛的变化:一项前瞻性研究。

Changes in back pain after percutaneous endoscopic lumbar discectomy and annuloplasty for lumbar disc herniation: a prospective study.

机构信息

Neurosurgery, Daegu Wooridul Spine Hospital, Daegu, Korea.

出版信息

Pain Med. 2011 Nov;12(11):1615-21. doi: 10.1111/j.1526-4637.2011.01250.x. Epub 2011 Oct 12.

Abstract

OBJECTIVE

Percutaneous endoscopic lumbar discectomy and annuloplasty (PELDA) is a minimally invasive spinal technique for lumbar disc herniation. Following discectomy, the relief of leg pain is common; however, the relief of back pain is less predictable. The purpose of this study was to evaluate changes in back pain and to examine the predisposing factors for postoperative back pain following PELDA.

DESIGN

In this prospective study, 58 patients with leg and back pain associated with disc herniation underwent PELDA. The patients were divided into two groups: unfavorable and favorable. Patients were defined as having unfavorable outcomes if the percentage improvement of back pain <50% or the postoperative Oswestry Disability Index (ODI) >20% at postoperative 24 months. The preoperative demographic, clinical, and radiologic factors for each group were statistically analyzed.

RESULTS

Fifty-two patients were enrolled in this study. The mean visual analog scale scores for back pain and the ODI scores significantly improved from 6.6 and 55.9% preoperatively to 2.5 and 12.7% at the 24-month follow-up. The surgical satisfaction rate was 78.4% at the final follow-up. Eighteen (34.6%) patients had unfavorable outcomes. Patients with advanced disc degeneration of operative levels had significantly worse outcomes than those with mild disc degeneration (odds ratio: 6.316, 95% confidence interval 1.25-31.86, P < 0.05). The severity of postoperative back pain was negatively correlated with surgical satisfaction (correlation coefficient: -0.564, P = 0.00).

CONCLUSION

PELDA can relieve back pain as well as leg pain through direct decompression and thermal ablation of the annular defect. Disc degeneration can be expected to influence clinical outcomes following PELDA.

摘要

目的

经皮内镜腰椎间盘切除术和环成形术(PELDA)是一种治疗腰椎间盘突出症的微创脊柱技术。椎间盘切除术后,腿部疼痛缓解较为常见,而背部疼痛缓解则较难预测。本研究旨在评估背部疼痛的变化,并探讨 PELDA 术后背部疼痛的相关因素。

设计

在这项前瞻性研究中,58 例下肢和背部疼痛伴椎间盘突出症的患者接受了 PELDA 治疗。患者分为两组:不良组和良好组。如果术后 24 个月背部疼痛改善百分比<50%或 Oswestry 功能障碍指数(ODI)>20%,则定义为不良结局。对每组的术前人口统计学、临床和影像学因素进行统计学分析。

结果

本研究共纳入 52 例患者。术后 24 个月,背部疼痛的视觉模拟评分和 ODI 评分分别从术前的 6.6 和 55.9%显著改善至 2.5 和 12.7%。最终随访时手术满意度为 78.4%。18 例(34.6%)患者出现不良结局。手术节段椎间盘退变程度较重的患者术后结局明显差于椎间盘退变程度较轻的患者(比值比:6.316,95%置信区间 1.25-31.86,P<0.05)。术后背部疼痛的严重程度与手术满意度呈负相关(相关系数:-0.564,P=0.00)。

结论

PELDA 可通过直接减压和环形缺陷的热消融来缓解腿部和背部疼痛。椎间盘退变可影响 PELDA 术后的临床结局。

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