Joseph C A, Begg N T, Stanwell-Smith R E, Magrath D I
PHLS Communicable Disease Surveillance Centre, London.
Br Med J (Clin Res Ed). 1987 Jul 18;295(6591):171-3. doi: 10.1136/bmj.295.6591.171.
Circulating antibodies to poliovirus were estimated in a group of 300 British and 84 foreign first year students who registered at the health centre of Nottingham University in 1984. Detectable antibodies to all three poliovirus serotypes were found in 212 (71%) of the British students but in only 47 (56%) of those from abroad. Most of the British students (280; 93%) had been born in 1965 or 1966, when uptake of poliomyelitis vaccine was declining. Immunisation histories showed that 10 British and 29 foreign students (3% and 35%) had no record of any immunisation; only five British and two foreign students, however, were negative for all three poliovirus serotypes. These findings provide evidence that a high proportion of British born people aged 18-29 have adequate circulating poliovirus antibodies despite incomplete immunisation schedules. Though this is reassuring, the absence of antibodies in some students and the lack of previous immunisation against poliomyelitis in 39 suggest that reinforcing doses of vaccine at the time of leaving school or beginning further education are still warranted, particularly for students from other countries. The findings also emphasise the need for accurate immunisation records.
1984年，在诺丁汉大学健康中心登记的300名英国一年级学生和84名外国一年级学生中，对脊髓灰质炎病毒的循环抗体进行了评估。在212名（71%）英国学生中发现了针对所有三种脊髓灰质炎病毒血清型的可检测抗体，而在外国学生中只有47名（56%）检测到。大多数英国学生（280名；93%）出生于1965年或1966年，当时脊髓灰质炎疫苗的接种率正在下降。免疫史显示，10名英国学生和29名外国学生（3%和35%）没有任何免疫记录；然而，只有5名英国学生和2名外国学生对所有三种脊髓灰质炎病毒血清型均呈阴性。这些发现表明，尽管免疫接种计划不完整，但很大一部分18 - 29岁出生在英国的人仍具有足够的循环脊髓灰质炎病毒抗体。尽管这令人放心，但一些学生没有抗体以及39人缺乏先前的脊髓灰质炎免疫接种表明，在离校或开始接受进一步教育时仍有必要加强疫苗接种，特别是对来自其他国家的学生。这些发现还强调了准确免疫记录的必要性。
