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欧盟/欧洲经济区的人口是否受到脊髓灰质炎的保护?

Is EU/EEA population protected from polio?

作者信息

Nijsten Dre, Carrillo-Santisteve P, Miglietta A, Ruitenberg J, Lopalco P L

机构信息

a European Centre for Disease Prevention and Control ; Stockholm , Sweden.

出版信息

Hum Vaccin Immunother. 2015;11(9):2123-31. doi: 10.1080/21645515.2015.1016673. Epub 2015 Apr 21.

Abstract

The WHO European Region has been declared polio-free since 2002. By 2010, inactivated polio vaccine (IPV) was the only polio vaccine in use in the EU/EEA for the primary vaccination of children. A systematic review of the literature on polio seroprevalence studies, complemented by the analysis of available vaccine coverage data, has been carried out with the aim of assessing the level of protection against polio in the European population. A total of 52 studies, with data from 14 out of the 31 EU/EEA countries, were included in the analysis. This systematic review shows that, overall, seroprevalence for PV1 and PV3 is high in most countries, although seroimmunity gaps have been detected in several birth cohorts. In particular, relatively low immunity status was found in some countries for individuals born in the 60's and 70's. Discrepancies between reported vaccination coverage and immunity levels have been also highlighted. Countries should make sure that their population is being vaccinated for polio to reduce the risk of local poliovirus transmission in case of importation. Moreover, assessing immunity status should be priority for those traveling to areas where wild polioviruses are still circulating.

摘要

自2002年以来,世界卫生组织欧洲区域已被宣布无脊髓灰质炎。到2010年,灭活脊髓灰质炎疫苗(IPV)是欧盟/欧洲经济区用于儿童初级疫苗接种的唯一脊髓灰质炎疫苗。为了评估欧洲人群针对脊髓灰质炎的保护水平,开展了一项关于脊髓灰质炎血清流行率研究的文献系统综述,并辅以对可用疫苗接种覆盖率数据的分析。该分析共纳入了52项研究,数据来自31个欧盟/欧洲经济区国家中的14个国家。这项系统综述表明,总体而言,大多数国家PV1和PV3的血清流行率较高,尽管在几个出生队列中发现了血清免疫差距。特别是,在一些国家,60年代和70年代出生的人群免疫状态相对较低。报告的疫苗接种覆盖率和免疫水平之间的差异也得到了凸显。各国应确保其民众接种脊髓灰质炎疫苗,以降低输入病例时脊髓灰质炎病毒在当地传播的风险。此外,对于前往野生脊髓灰质炎病毒仍在传播地区的人来说,评估免疫状态应成为优先事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6c9/4635704/a48bdf9980b1/khvi-11-09-1016673-g001.jpg

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