Center of Surgical & Molecular Tumor pathology, Department of Molecular Immunology & Toxicology, National Institute of Oncology, 1122 Rath Gy Street 7-9, Budapest, Hungary.
Immunotherapy. 2011 Oct;3(10):1131-7. doi: 10.2217/imt.11.114.
Biotherapy is widely considered as the fourth treatment modality for patients with cancer, and uses the constantly increasing knowledge in molecular biology, cell biology and immunology. Biotherapy uses naturally occurring biological molecules (e.g., cytokines and antibodies) or works by the manipulation of normal biological mechanisms (controlling or inhibiting tumor growth). Important achievements in anticancer drug development are immunotherapeutic strategies recently approved by the US FDA as well as clinical data of the cancer patients treated in clinical trials. There is a need to expand these novel cancer immunotherapeutic modalities for cancer patients all over the world. To meet that goal, it is essential to spread the information, to summarize the new clinical data and to draw the conclusions from the clinical and preclinical investigations. These frontline tasks can be well advanced by organizing international conferences in this domain in less scientifically developed countries, with a significant tumor burden statistics. Therefore, special efforts were done to organize the 2nd International Cancer Immunotherapy and Immunomonitoring Conference (CITIM-2011) in Hungary.
生物疗法被广泛认为是癌症患者的第四种治疗方式,它利用了分子生物学、细胞生物学和免疫学领域不断增长的知识。生物疗法使用天然存在的生物分子(例如细胞因子和抗体),或者通过操纵正常的生物学机制(控制或抑制肿瘤生长)来发挥作用。最近,美国食品和药物管理局(FDA)批准的免疫治疗策略以及临床试验中治疗的癌症患者的临床数据,是抗癌药物开发方面的重要成就。需要为全世界的癌症患者扩大这些新的癌症免疫治疗方式。为了实现这一目标,必须传播信息,总结新的临床数据,并从临床前和临床研究中得出结论。在肿瘤负担统计数据显著的欠发达科学国家组织该领域的国际会议,可以很好地推进这些前沿任务。因此,特别努力在匈牙利组织了第二届国际癌症免疫疗法和免疫监测会议(CITIM-2011)。