PharmIdeas Research and Consulting Inc., Oakville, ON, Canada.
Patient. 2011;4(4):259-65. doi: 10.2165/11587210-000000000-00000.
Pain is widespread, but has not yet been the focus of measurement in terms of patient preferences. This type of measure is needed for pharmacoeconomic analyses of pain medications.
Our objective was to compare scores from the Box Score (BS)-11 scale and the pain attribute of the Health Utilities Index (HUI)-3.
English- and/or French-speaking adult patients (aged ≥ 18 years) were recruited from pain clinics in four Canadian metropolitan areas (Toronto, Ottawa, Edmonton, Vancouver). Those providing informed consent completed both pain scales, assessing their average pain level over the previous 4 weeks. Kendall's Tau-b was calculated between score sets. Answers provided by patients were then used to determine the proportions of each of the BS-11 scores that mapped onto each of the five HUI-3 pain scores.
Six of the 516 completed questionnaires had missing information, leaving 510 for analysis. The average age of patients was 49.5 ± 11.9 years; 70% were female. Tau-b was reasonably large and statistically significant between the scales (τ = 0.685; p < 0.001). No patients had zero scores on BS-11, and two patients scored 1, yielding inconclusive results for that score. Eight of the remaining nine BS-11 scores mapped ≥ 60% onto HUI-3 pain scores. BS-11 scores 2 and 10 had the best mapping (88% and 94%, respectively).
BS-11 scores can be mapped onto the pain attribute of the HUI-3 with a high degree of correlation.
疼痛普遍存在,但尚未成为患者偏好测量的重点。这种类型的测量对于疼痛药物的药物经济学分析是必要的。
我们的目的是比较 Box Score (BS)-11 量表和 Health Utilities Index (HUI)-3 的疼痛属性评分。
从加拿大四个大都市地区(多伦多、渥太华、埃德蒙顿和温哥华)的疼痛诊所招募讲英语和/或法语的成年患者(年龄≥18 岁)。那些提供知情同意书的患者完成了两种疼痛量表,评估了他们过去 4 周的平均疼痛水平。计算了得分集之间的 Kendall's Tau-b。然后,根据患者的回答,确定 BS-11 分数中的每个分数与 HUI-3 疼痛分数中的每个分数的映射比例。
516 份完成的问卷中有 6 份有缺失信息,留下 510 份进行分析。患者的平均年龄为 49.5±11.9 岁;70%为女性。两种量表之间的 Tau-b 较大且具有统计学意义(τ=0.685;p<0.001)。没有患者的 BS-11 得分为零,有两个患者得分为 1,这导致该分数的结果不确定。BS-11 剩余 9 个分数中的 8 个映射到 HUI-3 疼痛分数的比例≥60%。BS-11 分数 2 和 10 的映射效果最好(分别为 88%和 94%)。
BS-11 分数可以与 HUI-3 的疼痛属性高度相关地映射。