College of Chemistry, Jilin University, Changchun 130012, PR China.
J Pharm Biomed Anal. 2012 Jan 25;58:141-5. doi: 10.1016/j.jpba.2011.09.011. Epub 2011 Sep 22.
In this paper, a novel chemiluminescence (CL) system, 2-phenyl-4, 5-di (2-furyl) imidazole (PDFI)-potassium ferricyanide, for the determination of terbutaline sulfate was described. The method was based on enhancement of CL emission of PDFI-potassium ferricyanide system in the presence of terbutaline sulfate. Under the optimum conditions, the enhanced chemiluminescence intensity is linearly related to the concentration of terbutaline sulfate. The proposed method has been successfully applied to the determination of terbutaline sulfate in bovine urine and pharmaceutical preparations with satisfactory results. Furthermore, the possible mechanism of chemiluminescence reaction was also discussed briefly.
本文描述了一种新的化学发光（CL）体系，2-苯基-4,5-二（2-呋喃基）咪唑（PDFI）-铁氰化钾，用于测定硫酸特布他林。该方法基于在硫酸特布他林存在下，PDFI-铁氰化钾体系的 CL 发射增强。在最佳条件下，增强的化学发光强度与硫酸特布他林的浓度呈线性关系。该方法已成功应用于牛尿和药物制剂中硫酸特布他林的测定，结果令人满意。此外，还简要讨论了化学发光反应的可能机制。
