Department of Urology, Ajou University School of Medicine, Suwon, Korea.
Urology. 2011 Dec;78(6):1369-72. doi: 10.1016/j.urology.2011.07.1379. Epub 2011 Oct 11.
To determine and compare autonomic dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
The subjects were 30-60 years old and had no known systemic disease. Electrocardiographic signals in the patients in the resting state were obtained from 59 patients with CP/CPPS (age 46.5 ± 7.02 years) and 94 healthy subjects (age 48.4 ± 5.96 years), and heart rate variability parameters were compared.
The standard deviation of the N-N interval (P < .001), square root of the mean squared differences of the successive N-N intervals (P = .004), total power (P = .004), very low frequency (P = .012), and high frequency (P < .001) were lower in the patients with CP/CPPS. However, no significant differences were found in the low frequency and low frequency/high frequency ratios.
Patients with CP/CPPS exhibited lower heart rate variability parameters compared with normal controls, with the exception of low frequency and low frequency/high frequency ratios. Possible differences in autonomic nervous system between those with CP/CPPS and normal healthy subjects could exist and autonomic dysfunction might be 1 of the causes that aggravates CP/CPPS.
确定并比较慢性前列腺炎/慢性骨盆疼痛综合征（CP/CPPS）患者的自主神经功能障碍。
研究对象为 30-60 岁且无已知系统性疾病的患者。从 59 例 CP/CPPS 患者（年龄 46.5±7.02 岁）和 94 例健康受试者（年龄 48.4±5.96 岁）中获取静息状态下的心电图信号，并比较心率变异性参数。
CP/CPPS 患者的 NN 间期标准差（P<.001）、相邻 NN 间期均方根差的平方根（P=.004）、总功率（P=.004）、极低频（P=.012）和高频（P<.001）较低。然而，低频和低频/高频比值无显著差异。
与正常对照组相比，CP/CPPS 患者的心率变异性参数较低，除低频和低频/高频比值外。CP/CPPS 患者与正常健康受试者之间可能存在自主神经系统的差异，自主神经功能障碍可能是 CP/CPPS 加重的原因之一。
