Department of Clinical Medicine and Prevention, Geriatric Clinic, University of Milan-Bicocca and San Gerardo Hospital, Monza, Italy.
J Am Med Dir Assoc. 2012 Mar;13(3):207-9. doi: 10.1016/j.jamda.2011.09.002. Epub 2011 Oct 12.
We report on an 80-year-old woman with Alzheimer's disease who presented with Takotsubo cardiomyopathy. As usual for this condition, our patient showed clinical symptoms of chest pain, electrocardiographic changes, elevated myocardial markers, and transient left ventricular apical ballooning in the absence of significant coronary artery disease. Because Takotsubo cardiomyopathy is frequently associated with emotional stress, which triggers an increase in circulating catecholamines, our case suggests that this event should not be neglected in Alzheimer's disease patients and promotes the adoption of a "prosthetic" approach for individuals with dementia.
我们报告了一例 80 岁老年女性阿尔茨海默病患者，其表现为 Takotsubo 心肌病。与这种情况通常一样，我们的患者表现出胸痛的临床症状、心电图改变、心肌标志物升高和短暂的左心室心尖球囊样变，而无明显的冠状动脉疾病。由于 Takotsubo 心肌病常与情绪压力相关，后者会导致循环儿茶酚胺增加，因此我们的病例提示，在阿尔茨海默病患者中不应忽视这种情况，并提倡对痴呆患者采用“假体”方法。
