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Chromosomal aberrations in primary Ewing sarcoma of the mandible.

作者信息

Manor Esther, Kapelushnik Joseph, Brennan Peter A, Bodner Lipa

机构信息

Institute of Human Genetics, Soroka University Medical Center, Ben Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Br J Oral Maxillofac Surg. 2012 Sep;50(6):574-6. doi: 10.1016/j.bjoms.2011.09.016. Epub 2011 Oct 11.

DOI:10.1016/j.bjoms.2011.09.016
PMID:21996574
Abstract

Ewing sarcoma is a malignant tumour of bone that is seen most often in children and young adults. The usual primary sites are the extremities, trunk, pelvis, and skull, and presentation in the mandible is rare. Cytogenetically it is characterised mainly by the translocation t(11;22)(q24;q12), which has an important role in the establishment of the clinical diagnosis. We report a 4-year-old boy with Ewing sarcoma of the mandible and the cytogenetic alterations that we found.

摘要

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