Department of Psychiatry and Psychotherapy, Christian Albrecht University, Kiel, Germany.
Am J Geriatr Psychiatry. 2012 Sep;20(9):782-8. doi: 10.1097/JGP.0b013e31823033da.
Recent evidence suggests that the sleep-dependent consolidation of declarative memory relies on the nonrapid eye movement rather than the rapid eye movement phase of sleep. In addition, it is known that aging is accompanied by changes in sleep and memory processes. Hence, the purpose of this study was to investigate the overnight consolidation of declarative memory in healthy elderly women.
Sleep laboratory of University.
Nineteen healthy elderly women (age range: 61-74 years).
We used laboratory-based measures of sleep. To test declarative memory, the Rey-Osterrieth Complex Figure Test was performed.
Declarative memory performance in elderly women was associated with Stage 2 sleep spindle density. Women characterized by high memory performance exhibited significantly higher numbers of sleep spindles and higher spindle density compared with women with generally low memory performance.
The data strongly support theories suggesting a link between sleep spindle activity and declarative memory consolidation.
最近的证据表明，陈述性记忆的睡眠依赖性巩固依赖于非快速眼动而非快速眼动睡眠阶段。此外，众所周知，衰老伴随着睡眠和记忆过程的变化。因此，本研究的目的是调查健康老年女性的陈述性记忆在夜间的巩固情况。
大学睡眠实验室。
19 名健康老年女性（年龄范围：61-74 岁）。
我们使用基于实验室的睡眠测量方法。为了测试陈述性记忆，我们进行了 Rey-Osterrieth 复杂图形测试。
老年女性的陈述性记忆表现与睡眠 2 期纺锤波密度有关。表现出高记忆性能的女性与一般记忆性能较低的女性相比，具有显著更多的睡眠纺锤波和更高的纺锤波密度。
这些数据强烈支持了睡眠纺锤波活动与陈述性记忆巩固之间存在联系的理论。
