Department of Psychology, University of Amsterdam, Weesperplein 4, 1018 XA Amsterdam, The Netherlands.
Learn Mem. 2012 Jun 14;19(7):264-7. doi: 10.1101/lm.026252.112.
Both sleep spindles and slow oscillations have been implicated in sleep-dependent memory consolidation. Whereas spindles occur during both light and deep sleep, slow oscillations are restricted to deep sleep, raising the possibility of greater consolidation-related spindle involvement during deep sleep. We assessed declarative memory retention over an interval containing a nap and determined spindle density for light and deep sleep separately. In deep sleep, spindle density was considerably higher and showed a strong and robust positive correlation with retention. This relation was absent for light sleep, suggesting that the potentiating effects of spindles are tied to their co-occurrence with slow oscillations.
睡眠纺锤波和慢波振荡都与睡眠依赖的记忆巩固有关。虽然纺锤波发生在浅睡和深睡期间，但慢波振荡仅发生在深睡期间，这表明在深睡期间，与记忆巩固相关的纺锤波参与程度更高。我们评估了包含小睡的时间段内的陈述性记忆保留情况，并分别确定了浅睡和深睡中的纺锤波密度。在深睡中，纺锤波密度要高得多，并且与保留呈强烈而稳健的正相关。在浅睡中则不存在这种关系，这表明纺锤波的增强效应与其与慢波振荡的同时发生有关。
