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轮状病毒全身感染导致猝死和轮状病毒非结构蛋白的检测

Sudden death from systemic rotavirus infection and detection of nonstructural rotavirus proteins.

机构信息

Kyoto Min-iren Chuo Hospital, 16-1 Nishinokyo-Kasuga-cho, Nakagyo-ku, Kyoto 604-8453, Japan.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4382-5. doi: 10.1128/JCM.01303-11. Epub 2011 Oct 12.

DOI:10.1128/JCM.01303-11
PMID:21998424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3232974/
Abstract

A 2.5-year-old girl died suddenly during the course of rotavirus gastroenteritis. The autopsy showed encephalopathy with rotavirus systemic infection. Here, we provide evidence of rotavirus replication in multiple organs. Our findings clarify that rotavirus infection in children can extend beyond the intestinal tract through viremia.

摘要

一名 2.5 岁女孩在轮状病毒胃肠炎期间突然死亡。尸检显示伴有轮状病毒全身感染的脑病。在此,我们提供了轮状病毒在多个器官中复制的证据。我们的发现阐明了轮状病毒感染可通过病毒血症从肠道以外部位扩散。

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本文引用的文献

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Analysis of rotavirus antigenemia and extraintestinal manifestations in children with rotavirus gastroenteritis.轮状病毒胃肠炎患儿轮状病毒血症及肠外表现分析
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Rotavirus antigenemia in children is associated with viremia.儿童轮状病毒血症与病毒血症相关。
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Arch Virol. 2005 Sep;150(9):1927-31. doi: 10.1007/s00705-005-0565-2. Epub 2005 Jun 15.
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