Volkow Nora D, Baler Ruben D, Normand Jacques L
National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd, Room 5274, MSC 9581, Bethesda, MD 20892, USA.
Curr HIV Res. 2011 Sep;9(6):393-5. doi: 10.2174/157016211798038605.
The stubbornly high incidence of new HIV infections belies the overwhelming evidence showing that sustained highly active antiretroviral therapy (HAART) has the power to dramatically reduce the spread of HIV infection and forever change the face of this devastating epidemic. One of the main contributors to this public health paradox is the ongoing HIV epidemic among substance users who contribute significantly to HIV infection rates through injection drug use and high-risk sexual behaviours. Current evidence clearly shows that, in order to fill this gap, we need to integrate substance abuse treatment with HIV treatment programmes and provide substance abusers with universal access to HIV treatment through a focussed effort to seek, test, treat, and retain hard-to-reach high risk individuals. These aims will require structural changes in the health care system to overcome many of the obstacles that have inhibited the merging of substance abuse treatment with HIV programmes for far too long.
新的艾滋病毒感染率居高不下,这与大量证据相悖,这些证据表明持续的高效抗逆转录病毒疗法(HAART)有能力大幅减少艾滋病毒感染的传播,并永远改变这一毁灭性流行病的面貌。造成这一公共卫生悖论的主要因素之一是吸毒者中持续存在的艾滋病毒疫情,他们通过注射吸毒和高危性行为对艾滋病毒感染率有重大影响。目前的证据清楚地表明,为了填补这一空白,我们需要将药物滥用治疗与艾滋病毒治疗方案相结合,并通过集中努力寻找、检测、治疗和留住难以接触到的高危个体,为药物滥用者提供普遍的艾滋病毒治疗机会。这些目标将需要医疗保健系统进行结构性变革,以克服长期以来阻碍药物滥用治疗与艾滋病毒方案合并的许多障碍。