以豚尾狒狒的光敏性癫痫作为药物研究模型。
Photosensitive epilepsy in Papio papio as a model for drug studies.
作者信息
Meldrum B S
出版信息
Electroencephalogr Clin Neurophysiol Suppl. 1978(34):317-22.
PMID:220003
Abstract
Photically-induced epilepsy in Papio papio provides a convenient model for assessing the efficacy and the acute neurological toxicity of new anticonvulsant drugs prior to clinical trial. Its drug sensitivity is broadly comparable to that of generalized seizures in man. It also shares some specific properties with syndromes of reflex epilepsy in man.
摘要
狒狒的光诱发性癫痫为在临床试验前评估新型抗惊厥药物的疗效和急性神经毒性提供了一个便利的模型。其药物敏感性与人类全身性癫痫发作的敏感性大致相当。它还与人类反射性癫痫综合征具有一些共同的特性。
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