Department of Prosthodontics and Oral Rehabilitation, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
Gerodontology. 2012 Jun;29(2):e845-50. doi: 10.1111/j.1741-2358.2011.00571.x. Epub 2011 Oct 17.
The aim of this study was to investigate the cross-sectional association of dental restorations with salivary cariogenic pathogens among the elderly to establish effective parameters of caries risk for this population.
Stimulated whole saliva was collected from 289 community-dwelling older adults (66.2 ± 3.9 years old) who had 20 or more teeth. Salivary levels of three cariogenic bacteria (Streptococcus mutans, Streptococcus sobrinus and lactobacilli) were estimated using quantitative polymerase chain reaction (real-time PCR) method.
The mean number of residual teeth was 26.4, and restored teeth with crowns, inlays and composite resin were 7.35, 3.88 and 0.68, respectively. The number of crowns correlated positively with salivary S. mutans, S. sobrinus and lactobacilli. Multiple linear regression analyses showed that the number of restored teeth with crowns was independently associated with salivary S. mutans, S. sobrinus and lactobacilli after controlling for age, gender, number of residual teeth and salivary flow rate. Salivary flow rate was independently associated with salivary S. mutans and lactobacilli.
The number of crowns had an association with salivary levels of cariogenic bacteria, suggesting that this parameter may be a caries risk indicator for the elderly population.
本研究旨在调查老年人的牙修复体与唾液致龋病原体之间的横断面关系，为该人群建立有效的龋病风险参数。
从 289 名居住在社区的老年成年人（66.2±3.9 岁）中收集了刺激全唾液，这些成年人有 20 颗或更多牙齿。使用定量聚合酶链反应（实时 PCR）方法估计了三种致龋细菌（变形链球菌、远缘链球菌和乳杆菌）的唾液水平。
平均剩余牙齿数为 26.4 颗，带冠、嵌体和复合树脂修复的牙齿数分别为 7.35、3.88 和 0.68 颗。牙冠数量与唾液中的 S. mutans、S. sobrinus 和乳杆菌呈正相关。多元线性回归分析表明，在控制年龄、性别、剩余牙齿数和唾液流速后，带冠修复牙的数量与唾液中的 S. mutans、S. sobrinus 和乳杆菌独立相关。唾液流速与唾液中的 S. mutans 和乳杆菌独立相关。
牙冠数量与唾液中致龋细菌的水平有关，这表明该参数可能是老年人群的龋病风险指标。
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