Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands.
Gastroenterol Res Pract. 2012;2012:147465. doi: 10.1155/2012/147465. Epub 2011 Oct 11.
Although little is known on the true prevalence of pancreatic cysts, physicians are currently more frequently confronted with pancreatic cysts because of the increasing use of sophisticated cross-sectional abdominal imaging. Cystic lesions of the pancreas comprise of a heterogeneous group of diagnostic entities, some of which are benign such as inflammatory pseudocysts or serous cystadenomas and do not require resection when asymptomatic. Others like mucinous cysts or intraductal papillary mucinous neoplasms (IPMN) have a malignant potential and in these cases surgical resection is often indicated. For this reason an adequate distinction between the various cysts is crucial to optimize management strategy. Different diagnostic methods that could be of value in the differentiation include radiologic imaging techniques such as CT, MR, and endosonography. In addition, fluid aspiration for cytopathology, tumormarkers or molecular analysis is widely used. Different guidelines are available but so far no optimal diagnostic algorithm exists. We summarize the epidemiology, classification, clinical presentation, diagnostics, management, and future perspectives.
尽管胰腺囊肿的确切患病率知之甚少，但由于腹部横断面成像技术的广泛应用，医生目前更频繁地遇到胰腺囊肿。胰腺囊性病变包括一组异质性的诊断实体，其中一些是良性的，如炎性假性囊肿或浆液性囊腺瘤，在无症状时不需要切除。另一些如黏液性囊肿或导管内乳头状黏液性肿瘤（IPMN）具有恶性潜能，在这些情况下，手术切除通常是指征。因此，对各种囊肿进行充分区分对于优化管理策略至关重要。有助于鉴别诊断的不同方法包括 CT、MR 和超声内镜等影像学技术。此外，广泛应用液体抽吸进行细胞学、肿瘤标志物或分子分析。目前已有不同的指南，但迄今为止尚无最佳的诊断算法。我们总结了流行病学、分类、临床表现、诊断、治疗和未来展望。
