正常山羊腰椎间盘软骨营养途径的磁共振动态对比增强成像研究。
Dynamic contrast enhanced-magnetic resonance imaging study of the nutrition pathway for lumbar intervertebral disk cartilage of normal goats.
机构信息
Department of Orthopedics, The First Affiliated Hospital of Xi'an Jiaotong University, China.
出版信息
Orthop Surg. 2011 May;3(2):106-12. doi: 10.1111/j.1757-7861.2011.00123.x.
OBJECTIVE
Study of the nutrition pathway for lumbar intervertebral disk cartilage of normal goats.
METHODS
Four lumbar intervertebral disks from each of eight 24-month-old goats (32 disks) were studied. After the goats had been anesthetized, signal intensity changes in the regions of interest (ROI) were observed by dynamic contrast enhanced magnetic resonance scanning. Before and after enhancement at the time points of 0, 5, 10, and 30 mins, and 1.0, 1.5, 2.0, 2.5, 3.0, and 3.5 hs, the ROI signal intensity was measured, and the time-signal intensity curve and peak times analyzed.
RESULTS
Signal intensity in the vertebral bodies reached a peak at 0 min and decreased quickly thereafter. Signal intensity in the cartilage endplate zones reached the first peak at 30 mins and then went down slightly before increasing to a second peak at 2 hs. Signal intensity in the nuclei pulposus was negative within 5 mins, increased slowly to a peak at 2 hs, and declined thereafter.
CONCLUSION
Nutrient metabolism of the lumbar intervertebral disks of normal goats occurs mainly through the cartilage end-plate pathway.
目的
研究正常山羊腰椎间盘软骨的营养途径。
方法
对 8 只 24 月龄山羊的 4 个腰椎间盘（共 32 个椎间盘）进行了研究。在山羊麻醉后，通过动态对比增强磁共振扫描观察感兴趣区（ROI）的信号强度变化。在增强前和增强后的 0、5、10、30 分钟以及 1.0、1.5、2.0、2.5、3.0 和 3.5 小时，测量 ROI 信号强度，并分析时间-信号强度曲线和峰值时间。
结果
椎体的信号强度在 0 分钟时达到峰值，随后迅速下降。软骨终板区的信号强度在 30 分钟时达到第一个峰值，然后略有下降，在 2 小时时达到第二个峰值。髓核的信号强度在 5 分钟内为阴性，缓慢增加至 2 小时达到峰值，随后下降。
结论
正常山羊腰椎间盘的营养代谢主要通过软骨终板途径进行。
Zotero 插件