Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
J Endourol. 2012 Jun;26(6):670-5. doi: 10.1089/end.2011.0372. Epub 2011 Oct 19.
The aim of our study was to compare early complication rates between the robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC) using a standardized reporting system.
From September 2008 to March 2011, 35 and 104 patients underwent ORC and RARC, respectively. Demographics and perioperative and complication data on all patients were reviewed retrospectively and compared between the two groups. All complications were categorized using a modified Clavien reporting system. We also sought to identify independent predictive factors of grade II or greater complications.
There were no significant differences between the ORC and RARC groups with regard to age, body mass index, American Society of Anesthesiologists score, clinical stage, surgical procedure history, or sex. The RARC group had more cases of ileal neobladder urinary diversion (P<0.001). We did not find any differences in terms of pathologic stage or length of stay. The ORC group had more grade II or greater complications (P=0.001), wound problems (P=0.043), multiple complications (P=0.014), greater estimated blood loss (EBL) (P<0.001), and needed more transfusions (P<0.001). A longer operative time was needed in the RARC group, however. Multivariate logistic regression analysis demonstrated that the ORC (P=0.045, odds ratio [95% confidence interval]=2.44 [1.02-5.85]), EBL (>500 mL, P=0.013, 2.75 [1.24-6.10]), and female sex (P=0.028, 4.06 [1.12-14.11]) were independent predictors of grade II or greater complications.
Our results showed that the RARC group was comparable to the ORC group with respect to complications using the Clavien reporting system. Further long-term and randomized trials are needed, however, because RARC is still not considered the standard therapy for bladder cancer.
本研究旨在使用标准化报告系统比较机器人辅助根治性膀胱切除术(RARC)与开放性根治性膀胱切除术(ORC)的早期并发症发生率。
2008 年 9 月至 2011 年 3 月,分别有 35 例和 104 例患者接受了 ORC 和 RARC。回顾性分析所有患者的人口统计学资料、围手术期资料和并发症数据,并比较两组之间的差异。所有并发症均采用改良的 Clavien 报告系统进行分类。我们还试图确定 II 级或更高级别并发症的独立预测因素。
两组患者在年龄、体重指数、美国麻醉医师协会评分、临床分期、手术史或性别方面无显著差异。RARC 组行回肠新膀胱尿流改道术的比例更高(P<0.001)。两组患者在病理分期或住院时间方面无差异。ORC 组 II 级或更高级别并发症(P=0.001)、伤口问题(P=0.043)、多种并发症(P=0.014)、估计失血量(EBL)更多(P<0.001)和需要输血的情况更多(P<0.001)。然而,RARC 组的手术时间更长。多变量逻辑回归分析显示,ORC(P=0.045,比值比[95%置信区间]=2.44[1.02-5.85])、EBL(>500 mL,P=0.013,2.75[1.24-6.10])和女性(P=0.028,4.06[1.12-14.11])是 II 级或更高级别并发症的独立预测因素。
我们的结果表明,使用 Clavien 报告系统,RARC 组与 ORC 组的并发症相当。然而,需要进一步的长期随机试验,因为 RARC 仍未被视为膀胱癌的标准治疗方法。