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舌前三分之二鳞状细胞癌与可摘义齿使用之间的关系:葡萄牙人群中的一项开创性研究。

Relationship between squamous cell carcinoma of the anterior two thirds of the tongue and removable denture use: a pioneer study in a Portuguese population.

作者信息

Alburqueque Rui, López-López Jose, Marí-Roig Antonio, Jané-Salas Enrique, Chimenos-Küstner Eduardo, Santos Jorge Rosa

机构信息

Odontotostomatology Department, Dental School, University of Barcelona, Catalonia, Spain.

出版信息

Braz Dent J. 2011;22(5):410-4. doi: 10.1590/s0103-64402011000500011.

DOI:10.1590/s0103-64402011000500011
PMID:22011898
Abstract

The aim of the study was to determine whether there is any relationship between the presence of removable dentures and squamous cell carcinoma of the anterior two thirds of the tongue in a Portuguese population. A retrospective cross-sectional study was conducted on patients with a biopsy-proven diagnosis of squamous cell carcinoma of the tongue, who were seen and treated at the Department of Head and Neck Surgery of the Portuguese Institute of Oncology 'Francisco Gentil', Lisbon, Portugal, during a 3-year period. Several factors were examined: gender, use of removable dentures, age, location of the lesion, and alcohol and tobacco consumption. One hundred and six cases were selected from the initial 151 cases, with a male:female ratio of 3:1 and the lateral borders being the most commonly affected site. The prevalence in both genders was between the sixth and seventh decade of life. Men were more likely to consume alcohol and tobacco than women, and no relationship was observed between denture use and presence of carcinoma of the tongue. In light of the data obtained, it may be considered that female use of a denture plays an important role, but it cannot be identified as a remarkable etiologic factor.

摘要

该研究的目的是确定在葡萄牙人群中,可摘义齿的使用与舌前三分之二鳞状细胞癌之间是否存在任何关联。对在葡萄牙里斯本“弗朗西斯科·根蒂尔”葡萄牙肿瘤研究所头颈外科就诊并接受治疗的、经活检证实为舌鳞状细胞癌的患者进行了一项回顾性横断面研究。研究考察了几个因素:性别、可摘义齿的使用情况、年龄、病变部位以及酒精和烟草的消费量。从最初的151例病例中选取了106例,男女比例为3:1,最常受累的部位是舌侧缘。两性的发病高峰均在60至70岁之间。男性比女性更易饮酒和吸烟,未观察到义齿使用与舌癌存在之间的关联。根据所获得的数据,可以认为女性使用义齿起到了重要作用,但不能将其确定为一个显著的病因因素。

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