Albuquerque Rui, López-López José, Marí-Roig Antonio, Jané-Salas Enric, Roselló-Llabrés Xavier, Santos Jorge Rosa
Department of Oral Medicine, University of Barcelona, Catalonia, Spain.
Braz Dent J. 2011;22(6):517-21. doi: 10.1590/s0103-64402011000600013.
There has been an increase in the incidence of carcinoma of the tongue, particularly among alcohol and tobacco non-users. However, the number of studies that would allow a better understanding of etiological factors and clinical features, particularly in the Portuguese population, is very limited. This study was based on patients with squamous cell carcinoma of the anterior two thirds of the tongue that were treated at the Department of Head and Neck Surgery of the "Instituto Portugues de Oncologia de Lisboa - Francisco Gentil" (IPOLFG) in Lisbon, Portugal, between January 1, 2001 and December 31, 2009. The patients were divided in alcohol and tobacco users and non-users in order to evaluate the differences between these 2 groups based on gender, age, tumor location, denture use, and tumor size, metastasis and stage. Of the 354 cases, 208 were users and 146 were non-users. The main location in both groups was the lateral border of the tongue. Denture use showed no significant effect in both study groups. It was possible to conclude that patients who did not drink or smoke were older and presented with smaller tumor size, lower incidence of ganglion metastasis and lower tumor stage compared with alcohol and tobacco users.
舌癌的发病率有所上升，尤其是在不饮酒和不吸烟的人群中。然而，能够更好地了解病因和临床特征的研究数量非常有限，特别是在葡萄牙人群中。本研究基于2001年1月1日至2009年12月31日期间在葡萄牙里斯本“里斯本弗朗西斯科·根蒂尔葡萄牙肿瘤研究所”（IPOLFG）头颈外科接受治疗的舌前三分之二鳞状细胞癌患者。为了评估这两组在性别、年龄、肿瘤位置、义齿使用情况以及肿瘤大小、转移和分期方面的差异，将患者分为饮酒和吸烟组以及不饮酒和不吸烟组。在354例病例中，208例为饮酒和吸烟者，146例为不饮酒和不吸烟者。两组的主要发病部位均为舌侧缘。义齿使用在两个研究组中均未显示出显著影响。可以得出结论，与饮酒和吸烟者相比，不饮酒或不吸烟的患者年龄更大，肿瘤尺寸更小，淋巴结转移发生率更低，肿瘤分期也更低。
