Master of Oral Medicine, University of Barcelona, Catalonia, Spain.
Med Oral Patol Oral Cir Bucal. 2012 Jul 1;17(4):e550-4. doi: 10.4317/medoral.17746.
The purpose of this study was to investigate the incidence of squamous cell carcinoma (SCC) of the anterior two thirds of the tongue in a population living in central and southern Portugal, all treated at Instituto Português de Oncologia de Lisboa, Francisco Gentil (IPOLFG).
This study was a retrospective review of all patients who had a histo- pathological diagnosis of SCC of the anterior two thirds of the tongue and had been treated in the Head and Neck Surgery Unit at the IPOLFG (Lisbon, Portugal), between 1st January 2001 and 31st December 2009. The risk factors evaluated were: gender; age; alcohol consumption; tobacco use; prosthesis use and the carcinoma site.
Of the 424 cases analysed, 71% were men. Mean age of occurrence was in 5th decade for males and the 6th decade for females, and the border of the tongue was the most common location. Alcohol consumption and tobacco had a lower impact in women, being the most common aetiological factors in the male population. No significant association was observed between patients and the use of a prosthesis.
In spite of the consumption of aohol and tobacco starting to decline in certain parts of the world, our findings showed both factors still have a significant impact in male population. Further research should be done to determine aetiological factors in females.
本研究旨在调查生活在葡萄牙中部和南部的人群中发生于舌前 2/3 部的鳞状细胞癌（SCC）的发病率，这些患者均在里斯本的葡萄牙肿瘤研究所（IPOLFG）的 Francisco Gentil 分院（IPOLFG）接受治疗。
这是一项对所有在葡萄牙肿瘤研究所（里斯本，葡萄牙）头颈外科接受治疗并具有舌前 2/3 部 SCC 组织病理学诊断的患者进行的回顾性研究，时间范围为 2001 年 1 月 1 日至 2009 年 12 月 31 日。评估的危险因素包括：性别；年龄；饮酒；吸烟；义齿使用情况以及癌灶位置。
在分析的 424 例病例中，71%为男性。男性发病的平均年龄在 50 岁左右，女性在 60 岁左右，且舌缘是最常见的发病部位。在女性中，酒精和烟草的摄入影响较小，而在男性人群中，这两种因素是最常见的病因。未观察到患者与义齿使用之间存在显著关联。
尽管在世界某些地区，酒精和烟草的消费开始下降，但我们的研究结果表明，这两个因素在男性人群中仍有显著影响。应进一步研究以确定女性的病因。
