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Emerg Infect Dis. 2011 Sep;17(9):1624-9. doi: 10.3201/eid1709.110338.
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Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009.2009 年加拿大猪群中流行的 H1N1 猪流感病毒的特性。
J Virol. 2011 Sep;85(17):8667-79. doi: 10.1128/JVI.00801-11. Epub 2011 Jun 22.
3
Molecular and antigenic characterization of triple-reassortant H3N2 swine influenza viruses isolated from pigs, turkey and quail in Canada.加拿大猪、火鸡和鹌鹑中分离的三重组 H3N2 猪流感病毒的分子和抗原特征。
Transbound Emerg Dis. 2011 Oct;58(5):394-401. doi: 10.1111/j.1865-1682.2011.01219.x. Epub 2011 Apr 5.
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Molecular characterization of pandemic H1N1 influenza viruses isolated from turkeys and pathogenicity of a human pH1N1 isolate in turkeys.从火鸡中分离出的大流行性H1N1流感病毒的分子特征及一株人源pH1N1分离株对火鸡的致病性
Avian Dis. 2010 Dec;54(4):1275-85. doi: 10.1637/9422-061410-Reg.1.
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Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment.大流行(H1N1)2009 流感病毒重配后可能致病性增加。
Emerg Infect Dis. 2011 Feb;17(2):200-8. doi: 10.3201/eid1702.101268.
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Novel H1N2 swine influenza reassortant strain in pigs derived from the pandemic H1N1/2009 virus.新型 H1N2 猪流感重组病毒源自大流行 H1N1/2009 病毒。
Vet Microbiol. 2011 May 5;149(3-4):472-7. doi: 10.1016/j.vetmic.2010.12.011. Epub 2010 Dec 14.
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Reassortment of pandemic H1N1/2009 influenza A virus in swine.猪流感病毒(H1N1/2009)的重配。
Science. 2010 Jun 18;328(5985):1529. doi: 10.1126/science.1189132.
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An investigation into human pandemic influenza virus (H1N1) 2009 on an Alberta swine farm.对艾伯塔省一个养猪场的2009年人类大流行性流感病毒(H1N1)的调查。
Can Vet J. 2009 Nov;50(11):1153-61.
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Genetic and pathobiologic characterization of pandemic H1N1 2009 influenza viruses from a naturally infected swine herd.从自然感染猪群中分离的大流行 H1N1 2009 流感病毒的遗传和病理生物学特征。
J Virol. 2010 Mar;84(5):2245-56. doi: 10.1128/JVI.02118-09. Epub 2009 Dec 16.
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A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.一条复杂的信息:鉴定一种从甲型流感病毒2号片段mRNA翻译而来的新型PB1相关蛋白。
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在加拿大的两个动物种群(水貂和猪)中出现了一种新的猪 H3N2 和大流行(H1N1)2009 流感 A 病毒重组体。

Emergence of a new swine H3N2 and pandemic (H1N1) 2009 influenza A virus reassortant in two Canadian animal populations, mink and swine.

机构信息

Service de Diagnostic, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, Québec, Canada J2S 7C6.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4386-90. doi: 10.1128/JCM.05676-11. Epub 2011 Oct 19.

DOI:10.1128/JCM.05676-11
PMID:22012020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3232932/
Abstract

A swine H3N2 (swH3N2) and pandemic (H1N1) 2009 (pH1N1) influenza A virus reassortant (swH3N2/pH1N1) was detected in Canadian swine at the end of 2010. Simultaneously, a similar virus was also detected in Canadian mink based on partial viral genome sequencing. The origin of the new swH3N2/pH1N1 viral genes was related to the North American swH3N2 triple-reassortant cluster IV (for hemagglutinin [HA] and neuraminidase [NA] genes) and to pH1N1 for all the other genes (M, NP, NS, PB1, PB2, and PA). Data indicate that the swH3N2/pH1N1 virus can be found in several pigs that are housed at different locations.

摘要

2010 年末,在加拿大的猪群中检测到了一种猪源 H3N2(swH3N2)和甲型流感病毒的 2009 年(pH1N1)大流行株(swH3N2/pH1N1)的重配病毒。同时,基于部分病毒基因组测序,在加拿大水貂中也检测到了类似的病毒。新的 swH3N2/pH1N1 病毒基因的起源与北美的 swH3N2 三重重配簇 IV(针对血凝素 [HA] 和神经氨酸酶 [NA] 基因)和 pH1N1 有关(针对所有其他基因 [M、NP、NS、PB1、PB2 和 PA])。数据表明,这种 swH3N2/pH1N1 病毒可在不同地点饲养的多只猪中找到。