Pharmacy Service, Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Clinics (Sao Paulo). 2011;66(10):1691-7. doi: 10.1590/s1807-59322011001000005.
To analyze the prevalence and types of prescribing and dispensing errors occurring with high-alert medications and to propose preventive measures to avoid errors with these medications.
The prevalence of adverse events in health care has increased, and medication errors are probably the most common cause of these events. Pediatric patients are known to be a high-risk group and are an important target in medication error prevention.
Observers collected data on prescribing and dispensing errors occurring with high-alert medications for pediatric inpatients in a university hospital. In addition to classifying the types of error that occurred, we identified cases of concomitant prescribing and dispensing errors.
One or more prescribing errors, totaling 1,632 errors, were found in 632 (89.6%) of the 705 high-alert medications that were prescribed and dispensed. We also identified at least one dispensing error in each high-alert medication dispensed, totaling 1,707 errors. Among these dispensing errors, 723 (42.4%) content errors occurred concomitantly with the prescribing errors. A subset of dispensing errors may have occurred because of poor prescription quality. The observed concomitancy should be examined carefully because improvements in the prescribing process could potentially prevent these problems.
The system of drug prescribing and dispensing at the hospital investigated in this study should be improved by incorporating the best practices of medication safety and preventing medication errors. High-alert medications may be used as triggers for improving the safety of the drug-utilization system.
分析高警示药物处方和配药错误的发生率和类型,并提出预防这些药物错误的措施。
医疗保健中不良事件的发生率有所增加,药物错误可能是这些事件的最常见原因。儿科患者是已知的高风险群体,是药物错误预防的重要目标。
观察者收集了一所大学医院儿科住院患者高警示药物处方和配药错误的数据。除了对发生的错误类型进行分类外,我们还确定了同时发生的处方和配药错误病例。
在开出的 705 种高警示药物中,有 632 种(89.6%)存在一种或多种处方错误,总计 1632 个错误。我们还在开出的每种高警示药物中发现了至少一个配药错误,总计 1707 个错误。在这些配药错误中,723 个(42.4%)内容错误与处方错误同时发生。由于处方质量差,可能会发生一部分配药错误。由于处方改进可能潜在地预防这些问题,应仔细检查所观察到的同时发生情况。
应通过纳入药物安全最佳实践和预防药物错误来改进所研究医院的药物处方和配药系统。高警示药物可以作为改善药物使用系统安全性的触发因素。