Nagotkar Leena, Shanbag Preeti, Mauskar Anupama, Zaki Syed Ahmed, Kumar Chaya A
Department of Pediatrics and Microbiology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India.
Indian J Crit Care Med. 2011 Jul;15(3):176-8. doi: 10.4103/0972-5229.84905.
Cryptococcus neoformans has a worldwide distribution. Meningoencephalitis is the most common manifestation of cryptococcosis. The outcome of a patient with cryptococcal infection depends on the immune status of the host. Patients with nephrotic syndrome are particularly susceptible to cryptococcal infection not only due to innate changes in their immune system but also because of the immunosuppressive agents used in the treatment. We report an 8-year-old boy with nephrotic syndrome, who developed cryptococcal meningitis and died of fulminant intracranial hypertension.
新型隐球菌在全球范围内均有分布。脑膜脑炎是隐球菌病最常见的表现形式。隐球菌感染患者的预后取决于宿主的免疫状态。肾病综合征患者特别容易发生隐球菌感染，这不仅是由于其免疫系统的固有变化，还因为治疗中使用了免疫抑制剂。我们报告了一名8岁的肾病综合征男孩，他患上了隐球菌性脑膜炎，并死于暴发性颅内高压。
