Department of Surgery, The University of Texas Health Science Center, Houston, TX 77030, USA.
Am J Surg. 2011 Dec;202(6):837-42. doi: 10.1016/j.amjsurg.2011.07.006. Epub 2011 Oct 19.
The need for emergent colon surgery is a common cause of severe sepsis/septic shock and mortality among surgical patients. We wanted to benchmark our outcomes against those of the National Surgical Quality Improvement Program (NSQIP). We hypothesized that having acute care surgeons to provide comprehensive perioperative care and rapid source control surgery would improve outcome.
We queried the 2005 to 2007 NSQIP dataset and our prospective database for patients with severe sepsis/septic shock requiring emergency colon surgery. Demographics, Acute Physiology and Chronic Health Evaluation II score, sepsis source, and hospital mortality data were obtained for all patients.
Both cohorts were similar with regard to age and sex. The overall mortality rate for patients in our dataset was 28.3% compared with 40.1% in the NSQIP dataset (P = .06). The average Acute Physiology and Chronic Health Evaluation II score for our patients was 31 ± 8.2 with a predicted mortality rate of 73% (P < .0001 when compared with actual mortality rate of 28.3%).
Patients with severe sepsis/septic shock requiring emergent colon surgery have a high mortality rate. Delivery of comprehensive emergency surgical care by acute care surgeons appears to improve survival.
急诊结肠手术的需求是外科患者发生严重脓毒症/感染性休克和死亡的常见原因。我们希望将我们的结果与国家外科质量改进计划(NSQIP)的结果进行基准比较。我们假设急性护理外科医生提供全面的围手术期护理和快速的源头控制手术会改善结果。
我们查询了 2005 年至 2007 年的 NSQIP 数据集和我们的前瞻性数据库,以获取需要紧急结肠手术治疗的严重脓毒症/感染性休克患者。对所有患者的人口统计学、急性生理学和慢性健康评估 II 评分、脓毒症源和医院死亡率数据进行了获取。
两个队列在年龄和性别方面相似。我们数据集患者的总体死亡率为 28.3%,而 NSQIP 数据集为 40.1%(P=.06)。我们患者的平均急性生理学和慢性健康评估 II 评分为 31 ± 8.2,预测死亡率为 73%(与实际死亡率 28.3%相比,P<.0001)。
需要紧急结肠手术治疗的严重脓毒症/感染性休克患者的死亡率很高。急性护理外科医生提供全面的紧急外科护理似乎可以提高生存率。