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Fast transcription rates of RNA polymerase II in human cells.人类细胞中 RNA 聚合酶 II 的快速转录速率。
EMBO Rep. 2011 Dec 1;12(12):1280-5. doi: 10.1038/embor.2011.196.
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The transcriptional cycle of HIV-1 in real-time and live cells.HIV-1在活细胞中的实时转录周期。
J Cell Biol. 2007 Oct 22;179(2):291-304. doi: 10.1083/jcb.200706018.
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RNA polymerase II transcription on the fast lane.RNA聚合酶II在快速通道上的转录。
Transcription. 2012 Jan-Feb;3(1):29-34. doi: 10.4161/trns.3.1.19147.
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In vivo dynamics of RNA polymerase II transcription.RNA聚合酶II转录的体内动力学
Nat Struct Mol Biol. 2007 Sep;14(9):796-806. doi: 10.1038/nsmb1280. Epub 2007 Aug 5.
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Measuring the kinetics of mRNA transcription in single living cells.测量单个活细胞中mRNA转录的动力学。
J Vis Exp. 2011 Aug 25(54):e2898. doi: 10.3791/2898.
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Measuring transcription dynamics in living cells using a photobleaching approach.使用光漂白方法测量活细胞中的转录动力学。
Methods. 2017 May 1;120:58-64. doi: 10.1016/j.ymeth.2017.04.007. Epub 2017 Apr 21.
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RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination.RNA 聚合酶 II CTD 磷酸酶 Rtr1 精细调节转录终止。
PLoS Genet. 2020 Mar 18;16(3):e1008317. doi: 10.1371/journal.pgen.1008317. eCollection 2020 Mar.
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The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing.RNA 聚合酶 II 在共转录剪接过程中延伸的体内动力学。
PLoS Biol. 2011 Jan 11;9(1):e1000573. doi: 10.1371/journal.pbio.1000573.
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Single-site transcription rates through fitting of ensemble-averaged data from fluorescence recovery after photobleaching: a fat-tailed distribution.通过对光漂白后荧光恢复的总体平均数据进行拟合得到的单位点转录速率：一种厚尾分布。
Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Sep;92(3):032715. doi: 10.1103/PhysRevE.92.032715. Epub 2015 Sep 17.
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RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.RNA 靶向核糖生成因子 WDR43 到染色质以进行转录和多能性控制。
Mol Cell. 2019 Jul 11;75(1):102-116.e9. doi: 10.1016/j.molcel.2019.05.007. Epub 2019 May 22.
引用本文的文献
1
Co-transcriptional splicing facilitates transcription of gigantic genes.共转录剪接促进巨大基因的转录。
PLoS Genet. 2024 Jun 13;20(6):e1011241. doi: 10.1371/journal.pgen.1011241. eCollection 2024 Jun.
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Following the tracks: How transcription factor binding dynamics control transcription.追踪转录因子结合动力学：如何控制转录。
Biophys J. 2022 May 3;121(9):1583-1592. doi: 10.1016/j.bpj.2022.03.026. Epub 2022 Mar 23.
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Slow nucleosome dynamics set the transcriptional speed limit and induce RNA polymerase II traffic jams and bursts.缓慢的核小体动力学设定了转录的速度极限，并诱导 RNA 聚合酶 II 交通堵塞和爆发。
PLoS Comput Biol. 2022 Feb 10;18(2):e1009811. doi: 10.1371/journal.pcbi.1009811. eCollection 2022 Feb.
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RNA polymerase II speed: a key player in controlling and adapting transcriptome composition.RNA 聚合酶 II 速度：控制和适应转录组组成的关键因素。
EMBO J. 2021 Aug 2;40(15):e105740. doi: 10.15252/embj.2020105740. Epub 2021 Jul 13.
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Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene.改变转录因子结合可揭示基本基因的全面转录动力学。
Nucleic Acids Res. 2021 Jun 21;49(11):6249-6266. doi: 10.1093/nar/gkab443.
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Entropic Competition between Supercoiled and Torsionally Relaxed Chromatin Fibers Drives Loop Extrusion through Pseudo-Topologically Bound Cohesin.超螺旋与扭转松弛染色质纤维之间的熵竞争通过假拓扑结合的黏连蛋白驱动环挤压。
Biology (Basel). 2021 Feb 7;10(2):130. doi: 10.3390/biology10020130.
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RNA-Mediated Feedback Control of Transcriptional Condensates.RNA 介导的转录凝聚物反馈控制。
Cell. 2021 Jan 7;184(1):207-225.e24. doi: 10.1016/j.cell.2020.11.030. Epub 2020 Dec 16.
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Changes of Gene Expression in Euglena gracilis Obtained During the 29 DLR Parabolic Flight Campaign.在 29 次 DLR 抛物线飞行任务期间获得的眼虫藻基因表达变化。
Sci Rep. 2019 Oct 3;9(1):14260. doi: 10.1038/s41598-019-50611-4.
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Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis.卫星 DNA 富含巨型内含子的独特基因表达程序在果蝇精子发生过程中。
PLoS Genet. 2019 May 9;15(5):e1008028. doi: 10.1371/journal.pgen.1008028. eCollection 2019 May.
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Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes.评价可能导致抗原变异的非洲锥虫 DNA 损伤触发机制。
PLoS Pathog. 2018 Nov 15;14(11):e1007321. doi: 10.1371/journal.ppat.1007321. eCollection 2018 Nov.
本文引用的文献
1
Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function.鉴定 HIV-1 RNA 相关蛋白组表明 Matrin 3 是 Rev 功能的核辅助因子。
Retrovirology. 2011 Jul 20;8:60. doi: 10.1186/1742-4690-8-60.
2
Nuclear positional control of HIV transcription in 4D.4D 中 HIV 转录的核定位控制。
Nucleus. 2010 Jan-Feb;1(1):8-11. doi: 10.4161/nucl.1.1.10136.
3
A transgenic mouse for in vivo detection of endogenous labeled mRNA.用于体内检测内源性标记 mRNA 的转基因小鼠。
Nat Methods. 2011 Feb;8(2):165-70. doi: 10.1038/nmeth.1551. Epub 2011 Jan 16.
4
Single-allele analysis of transcription kinetics in living mammalian cells.活哺乳动物细胞中转录动力学的单等位基因分析。
Nat Methods. 2010 Aug;7(8):631-3. doi: 10.1038/nmeth.1482. Epub 2010 Jul 18.
5
Real-time imaging of the HIV-1 transcription cycle in single living cells.在单个活细胞中实时成像 HIV-1 转录周期。
Methods. 2011 Jan;53(1):62-7. doi: 10.1016/j.ymeth.2010.06.015. Epub 2010 Jun 25.
6
Tracking rates of transcription and splicing in vivo.体内转录和剪接速率的追踪
Nat Struct Mol Biol. 2009 Nov;16(11):1123-4. doi: 10.1038/nsmb1109-1123.
7
A wave of nascent transcription on activated human genes.激活的人类基因上的新生转录波。
Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18357-61. doi: 10.1073/pnas.0902573106. Epub 2009 Oct 13.
8
Rates of in situ transcription and splicing in large human genes.大型人类基因中的原位转录和剪接速率。
Nat Struct Mol Biol. 2009 Nov;16(11):1128-33. doi: 10.1038/nsmb.1666. Epub 2009 Oct 11.
9
Transcriptional competence of the integrated HIV-1 provirus at the nuclear periphery.整合的 HIV-1 前病毒在核周的转录能力。
EMBO J. 2009 Aug 5;28(15):2231-43. doi: 10.1038/emboj.2009.141. Epub 2009 May 28.
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Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous gene.人类免疫缺陷病毒1的基因内转录顺式激活不会导致内源性基因的等位基因特异性抑制。
Retrovirology. 2008 Nov 4;5:98. doi: 10.1186/1742-4690-5-98.
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