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[中药注射剂的改进与提升]

[Improvement and enhancement of traditional Chinese medicine injections].

作者信息

Li Yikui, Zhang Jinyan

机构信息

Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2011 Jul;36(14):1905-9.

Abstract

Compared to oral administrations, traditional Chinese medicine (TCM) injections act more rapidly and stronger, which is good for the treatment of acute or complicated diseases and makes up for the deficiencies of the oral ways. As an innovative dosage form which combines the modern pharmaceutical technology with the TCM, it represents the spirit of improvement and enhancement. With the expansion of clinical applications and adverse reactions or even death caused by individual dosages, TCM injections are receiving concerns from all fields of society and facing tremendous challenges and pressures. Some even suggested the cancellation. This study discussed the background, current situation and the reasons for the occurrence of adverse reactions. Taking Houttuynia injection as an example, it introduced the principle of improvement and described in detail the ideas and methods for it, which provided some reference for the improvement and enhancement of the TCM injections and reduced the safety risks of TCM injections to minimum.

摘要

与口服给药相比,中药注射剂作用更快更强,有利于急性或复杂疾病的治疗,弥补了口服给药方式的不足。作为一种将现代制药技术与中药相结合的创新剂型,它体现了改进与提升的精神。随着临床应用范围的扩大以及个别剂量引发的不良反应甚至死亡事件的出现,中药注射剂受到了社会各界的关注,面临着巨大的挑战和压力。有人甚至建议取消。本研究探讨了其背景、现状以及不良反应发生的原因。以鱼腥草注射液为例,介绍了改进的原则,并详细阐述了改进的思路和方法,为中药注射剂的改进与提升提供了一定参考,将中药注射剂的安全风险降至最低。

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