[皱叶酸模化学成分的研究]

[Study on the chemical constituents of Rumex patientia].

作者信息

Liu Jing, Xia Zhong-ting, Zhou Gui-rong, Zhang Lan-lan, Kong Ling-yi

机构信息

Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.

出版信息

Zhong Yao Cai. 2011 Jun;34(6):893-5.

PMID:22017004

Abstract

OBJECTIVE

To study the chemical constituents of roots of Rumex patientia.

METHODS

The compounds were separated and purified by silica column chromatopraphy, Sephadex LH-20 and identified by several spectroscopic methods.

RESULTS

Seven constituents were identified as nepodin (1), nepodin-8-O-beta-D-glucopyranoside (2), chrysophanol-8-O-beta-D-glucopyranoside (3), emodin-6-O-beta-D-glucopyranoside (4), emodin-8-O-beta-D-glucopyranoside (5), 1, 3, 5-trihydroxy-7-methylanthraquinone (6), physcion-8-O-beta-D-glucopyranoside (7), respectively.

CONCLUSION

Compound 1 is isolated from this plant for the first time and compound 6 is isolated from Rumex L. for the first time.

摘要

目的

研究皱叶酸模根的化学成分。

方法

采用硅胶柱色谱、葡聚糖凝胶LH - 20对化合物进行分离纯化，并通过多种光谱方法进行鉴定。

结果

鉴定出7种成分，分别为尼泊尔蓼素（1）、尼泊尔蓼素-8 - O-β - D - 吡喃葡萄糖苷（2）、大黄酚-8 - O-β - D - 吡喃葡萄糖苷（3）、大黄素-6 - O-β - D - 吡喃葡萄糖苷（4）、大黄素-8 - O-β - D - 吡喃葡萄糖苷（5）、1, 3, 5 - 三羟基-7 - 甲基蒽醌（6）、大黄素甲醚-8 - O-β - D - 吡喃葡萄糖苷（7）。