钯(IV)中心的 C-H 键活化。
C-H bond activation at palladium(IV) centers.
机构信息
University of Michigan, Department of Chemistry, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
出版信息
J Am Chem Soc. 2011 Nov 16;133(45):18022-5. doi: 10.1021/ja2051099. Epub 2011 Oct 21.
Abstract
This communication describes the first observation and study of C-H activation at a Pd(IV) center. This transformation was achieved by designing model complexes in which the rate of reductive elimination is slowed relative to that of the desired C-H activation process. Remarkably, the C-H activation reaction can proceed under mild conditions and with complementary site selectivity to analogous transformations at Pd(II). These results provide a platform for incorporating this new reaction as a step in catalytic processes.
摘要
本通讯描述了首例钯(IV)中心 C-H 键活化的观察和研究。通过设计模型配合物，使还原消除的速率相对于所需的 C-H 活化过程减慢，从而实现了这种转化。值得注意的是，C-H 活化反应可以在温和条件下进行，并具有与 Pd(II) 类似转化互补的位点选择性。这些结果为将这一新反应纳入催化过程提供了一个平台。
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